This database contains 9 abstracts archived under the term: "BMJ (Clinical Research Ed.)"
Objective: To assess the efficacy at 12 months of an early psychosocial counselling and support programme for outpatients with mild Alzheimer’s disease and their primary care givers.; Design: Multicentre, randomised, controlled, rater blinded trial.; Setting: Primary care and memory clinics in five Danish districts.; Participants: 330 outpatients with mild Alzheimer’s disease and their 330 primary […]
Objective: To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners.; Design: Multicentre randomised controlled trial.; Setting: Nine memory clinics and 159 general practitioners in the Netherlands.; Participants: 175 patients with a new diagnosis of mild to moderate dementia living in the community and their informal […]
Objective: To determine the effect of discontinuing antidepressant treatment in people with dementia and neuropsychiatric symptoms.; Design: Double blind, randomised, parallel group, placebo controlled trial.; Setting: Norwegian nursing homes; residents recruited by 16 study centres in Norway from August 2008 to June 2010.; Participants: 128 patients with Alzheimer’s disease, dementia or vascular dementia, and neuropsychiatric […]
Objective: To test the effectiveness of a comprehensive specific care plan in decreasing the rate of functional decline in patients with mild to moderate Alzheimer’s disease compared with usual care in memory clinics.; Design: Cluster randomised trial.; Setting: 50 memory clinics in France.; Participants: Patients with Alzheimer’s disease (mini-mental state examination score 12-26). 1131 patients […]
Objective: To evaluate the effect of a video decision support tool on the preferences for future medical care in older people if they develop advanced dementia, and the stability of those preferences after six weeks.; Design: Randomised controlled trial conducted between 1 September 2007 and 30 May 2008. Setting Four primary care clinics (two geriatric […]
Objective: To assess whether a manual based coping strategy compared with treatment as usual reduces depression and anxiety symptoms in carers of family members with dementia.; Design: Randomised, parallel group, superiority trial.; Setting: Three mental health community services and one neurological outpatient dementia service in London and Essex, UK.; Participants: 260 carers of family members […]
Objective: To assess whether the START (STrAtegies for RelatTives) intervention added to treatment as usual is cost effective compared with usual treatment alone.; Design: Cost effectiveness analysis nested within a pragmatic randomised controlled trial.; Setting: Three mental health and one neurological outpatient dementia service in London and Essex, UK.; Participants: Family carers of people with […]
Objective: To determine whether a systematic approach to the treatment of pain can reduce agitation in people with moderate to severe dementia living in nursing homes.; Design: Cluster randomised controlled trial.; Setting: 60 clusters (single independent nursing home units) in 18 nursing homes within five municipalities of western Norway.; Participants: 352 residents with moderate to […]
Objective: To quantify the unintended effects of statins according to type, dose, and duration of use.; Design: Prospective open cohort study using routinely collected data.; Setting: 368 general practices in England and Wales supplying data to the QResearch database.; Participants: 2 004 692 patients aged 30-84 years of whom 225 922 (10.7%) were new users […]
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