Bauer, Lisa, Pozehl, Bunny, Hertzog, Melody, Johnson, Julene, Zimmerman, Lani, Filipi, Mary

Background: Cognitive impairment is a recognized consequence of heart failure; however, there are no neuropsychological batteries with documented psychometric data in the chronic heart failure population.; Aims: To document the psychometric properties of a brief neuropsychological battery in a chronic heart failure sample.; Methods: The Repeatable Battery for the Assessment of Neuropsychological Status, Trail Making […]

Barnes, Lisa L., Mendes de Leon, Carlos F., Bienias, Julia L., Wilson, Robert S., Everson-Rose, Susan A., Evans, Denis A.

Objective: To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race.; Methods: Over 4800 persons from a defined community in Chicago completed up to three structured interviews at approximately 3 year intervals over a […]

Ashford, J. Wesson, Gere, Emily, Bayley, Peter J.

Memory function generally deteriorates with age, and memory impairments are a common symptom of serious illness such as dementia. Although screening tests are widely used throughout Medicine, they are not yet commonly used to detect memory impairments. The objective of this study was to characterize an audience-based memory test suitable for administration to a large […]

Aronson, Stephen, Baelen, Bart Van, Kavanagh, Shane, Schwalen, Susanne

Background: Galantamine (hydrobromide), a reversible acetylcholinesterase inhibitor and allosteric nicotinic receptor modulator, slows cognitive and functional decline in mild to moderate dementia of the Alzheimer’s type. Although several drugs are indicated for mild to moderate Alzheimer’s disease (AD), no published study has separately analysed mild and moderate AD subgroups to assess the effect of dosage.; […]

Anderson-Hanley, Cay, Arciero, Paul J., Brickman, Adam M., Nimon, Joseph P., Okuma, Naoko, Westen, Sarah C., Merz, Molly E., Pence, Brandt D., Woods, Jeffrey A., Kramer, Arthur F., Zimmerman, Earl A.

Background: Dementia cases may reach 100 million by 2050. Interventions are sought to curb or prevent cognitive decline. Exercise yields cognitive benefits, but few older adults exercise. Virtual reality-enhanced exercise or “exergames” may elicit greater participation.; Purpose: To test the following hypotheses: (1) stationary cycling with virtual reality tours (“cybercycle”) will enhance executive function and […]

Anderson, Steven W., Aksan, Nazan, Dawson, Jeffrey D., Uc, Ergun Y., Johnson, Amy M., Rizzo, Matthew

Decline in cognitive abilities can be an important contributor to the driving problems encountered by older adults, and neuropsychological assessment may provide a practical approach to evaluating this aspect of driving safety risk. The purpose of the present study was to evaluate several commonly used neuropsychological tests in the assessment of driving safety risk in […]

Aman, Edris, Thomas, David R.

Background: Several studies have shown an improvement in depression, activities of daily living, and agitation in cognitively impaired subjects who undergo a long-term exercise program. These studies have not considered the short-term effects of exercise.; Objectives: The purpose of this study was to investigate the short-term effects of a limited, supervised exercise program on agitation, […]

Adhikari, T., Piatti, A., Luggen, M.

Background: Cognitive dysfunction (CD) is among the most common neuropsychiatric manifestations of systemic lupus erythematosus (SLE). There are two methods which have been used to detect CD in patients with SLE: traditional neuropsychological tests (NPT) and the Automated Neuropsychological Assessment Metrics (ANAM). Both are time-consuming and neither is readily available for screening purposes.; Purpose: The […]