This database contains 106 studies, archived under the term: "Service use or cost reductions (incl. hospital use reduction, care home admission delay)"
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Effectiveness of a specific care plan in patients with Alzheimer’s disease: cluster randomised trial (PLASA study)
Nourhashemi, Fati,
Andrieu, Sandrine,
Gillette-Guyonnet, Sophie,
Giraudeau, Bruno,
Cantet, Christelle,
Coley, Nicola,
Vellas, Bruno
Objective: To test the effectiveness of a comprehensive specific care plan in decreasing the rate of functional decline in patients with mild to moderate Alzheimer’s disease compared with usual care in memory clinics.; Design: Cluster randomised trial.; Setting: 50 memory clinics in France.; Participants: Patients with Alzheimer’s disease (mini-mental state examination score 12-26). 1131 patients […]
Evidence-based interventions in dementia: A pragmatic cluster-randomised trial of an educational intervention to promote earlier recognition and response to dementia in primary care (EVIDEM-ED)
Iliffe, Steve,
Wilcock, Jane,
Griffin, Mark,
Jain, Priya,
Thuné-Boyle, Ingela,
Koch, Tamar,
Lefford, Frances
Background: The National Dementia Strategy seeks to enhance general practitioners’ diagnostic and management skills in dementia. Early diagnosis in dementia within primary care is important as this allows those with dementia and their family care networks to engage with support services and plan for the future. There is, however, evidence that dementia remains under-detected and […]
Cost-effectiveness of post-diagnosis treatment in dementia coordinated by Multidisciplinary Memory Clinics in comparison to treatment coordinated by general practitioners: an example of a pragmatic trial
Meeuwsen, E. J.,
German, P.,
Melis, R. J. F.,
Adang, E. M.,
Golüke-Willemse, G. A.,
Krabbe, P. F.,
de Leest, B. J.,
van Raak, F. H. J. M.,
Schölzel-Dorenbos, C. J. M.,
Visser, M. C.,
Wolfs, C. A.,
Vliek, S.,
Rikkert, M. G. M. Olde
Background: With the rising number of dementia patients with associated costs and the recognition that there is room for improvement in the provision of dementia care, the question arises on how to efficiently provide high quality dementia care.; Objective: To describe the design of a study to determine multidisciplinary memory clinics’ (MMC) effectiveness and cost-effectiveness […]
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer’s disease – a multicentre RCT
Jones, Rob,
Sheehan, Bart,
Phillips, Patrick,
Juszczak, Ed,
Adams, Jessica,
Baldwin, Ashley,
Ballard, Clive,
Banerjee, Sube,
Barber, Bob,
Bentham, Peter,
Brown, Richard,
Burns, Alistair,
Dening, Tom,
Findlay, David,
Gray, Richard,
Griffin, Mary,
Holmes, Clive,
Hughes, Alan,
Jacoby, Robin,
Johnson, Tony,
Jones, Roy,
Knapp, Martin,
Lindesay, James,
McKeith, Ian,
McShane, Rupert,
Macharouthu, Ajay,
O'Brien, John,
Onions, Caroline,
Passmore, Peter,
Raftery, James,
Ritchie, Craig,
Howard, Rob
Background: Alzheimer’s disease (AD) is the commonest cause of dementia. Cholinesterase inhibitors, such as donepezil, are the drug class with the best evidence of efficacy, licensed for mild to moderate AD, while the glutamate antagonist memantine has been widely prescribed, often in the later stages of AD. Memantine is licensed for moderate to severe dementia […]
Dementia care initiative in primary practice: study protocol of a cluster randomized trial on dementia management in a general practice setting
Holle, Rolf,
Grässel, Elmar,
Ruckdäschel, Stefan,
Wunder, Sonja,
Mehlig, Hilmar,
Marx, Peter,
Pirk, Olaf,
Butzlaff, Martin,
Kunz, Simone,
Lauterberg, Jörg
Background: Current guidelines for dementia care recommend the combination of drug therapy with non-pharmaceutical measures like counselling and social support. However, the scientific evidence concerning non-pharmaceutical interventions for dementia patients and their informal caregivers remains inconclusive. Targets of modern comprehensive dementia care are to enable patients to live at home as long and as independent […]
Evaluation of a brief educational program for dementia carers: the AENEAS study
Objective: To evaluate the efficacy of a practical, easily implemented, educational intervention in group format for informal carers of persons with dementia.; Methods: Multi-centre, randomised, controlled, single-blind trial involving 292 family caregivers of patients with moderate dementia in Alzheimer’s disease.; Results: Participants valued program components which had a practical impact on their caring role. The […]