This database contains 155 studies, archived under the term: "Quality of Life of Person With Dementia"
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Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT)
Clare, Linda,
Bayer, Antony,
Burns, Alistair,
Corbett, Anne,
Jones, Roy,
Knapp, Martin,
Kopelman, Michael,
Kudlicka, Aleksandra,
Leroi, Iracema,
Oyebode, Jan,
Pool, Jackie,
Woods, Bob,
Whitaker, Rhiannon
Background: Preliminary evidence suggests that goal-oriented cognitive rehabilitation (CR) may be a clinically effective intervention for people with early-stage Alzheimer’s disease, vascular or mixed dementia and their carers. This study aims to establish whether CR is a clinically effective and cost-effective intervention for people with early-stage dementia and their carers.; Methods/design: In this multi-centre, single-blind […]
Acupressure in insomnia and other sleep disorders in elderly institutionalized patients suffering from Alzheimer’s disease
Simoncini, M.,
Gatti, A.,
Quirico, P. E.,
Balla, S.,
Capellero, B.,
Obialero, R.,
D'Agostino, S.,
Sandri, N.,
Pernigotti, L. M.
BACKGROUND: Sleep disorders are very common in elderly institutionalized people with dementia and acupressure recently has been associated with conventional medicine in their treatment. AIMS: Exploring the effectiveness of acupressure for the treatment of insomnia and other sleep disturbances and we want to show that the acupressure treatment is feasible also in elderly resident patients. […]
The effect of regular walks on various health aspects in older people with dementia: protocol of a randomized-controlled trial
Background: Physical activity has proven to be beneficial for physical functioning, cognition, depression, anxiety, rest-activity rhythm, quality of life (QoL), activities of daily living (ADL) and pain in older people. The aim of this study is to investigate the effect of walking regularly on physical functioning, the progressive cognitive decline, level of depression, anxiety, rest-activity […]
REMCARE: reminiscence groups for people with dementia and their family caregivers – effectiveness and cost-effectiveness pragmatic multicentre randomised trial
Woods, R. T.,
Bruce, E.,
Edwards, R. T.,
Elvish, R.,
Hoare, Z.,
Hounsome, B.,
Keady, J.,
Moniz-Cook, E. D.,
Orgeta, V.,
Orrell, M.,
Rees, J.,
Russell, I. T.
Objectives: The aim of the REMiniscence groups for people with dementia and their family CAREgivers (REMCARE) study was to assess the effectiveness and cost-effectiveness of joint reminiscence groups for people with dementia and their family caregivers as compared with usual care.; Design: A multicentre, pragmatic randomised controlled trial with two parallel arms – an intervention […]
Preventing loss of independence through exercise (PLIE): a pilot clinical trial in older adults with dementia
Barnes, D. E.,
Mehling, W.,
Wu, E.,
Beristianos, M.,
Yaffe, K.,
Skultety, K.,
Chesney, M. A.
BACKGROUND: Current dementia medications have small effect sizes, many adverse effects and do not change the disease course. Therefore, it is critically important to study alternative treatment strategies. The goal of this study was to pilot-test a novel, integrative group exercise program for individuals with mild-to-moderate dementia called Preventing Loss of Independence through Exercise (PLIE), […]
The Indiana University Cognitive Health Outcomes Investigation of the Comparative Effectiveness of dementia screening (CHOICE) study: study protocol for a randomized controlled trial
Fowler, Nicole R.,
Harrawood, Amanda,
Frame, Amie,
Perkins, Anthony J.,
Gao, Sujuan,
Callahan, Christopher M.,
Sachs, Greg A.,
French, Dustin D.,
Boustani, Malaz A.
Background: Dementia affects over 4 million people in the US and is frequently unrecognized and underdiagnosed in primary care. Routine dementia screening in primary care is not recommended by the US Preventive Services Task Force due to lack of empirical data on the benefits and harms of screening. This trial seeks to fill this gap […]
Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): study protocol for a randomized controlled trial
Cooper, Sally-Ann,
Caslake, Muriel,
Evans, Jonathan,
Hassiotis, Angela,
Jahoda, Andrew,
McConnachie, Alex,
Morrison, Jill,
Ring, Howard,
Starr, John,
Stiles, Ciara,
Sullivan, Frank
Background: Early-onset dementia is common in Down syndrome adults, who have trisomy 21. The amyloid precursor protein gene is on chromosome 21, and so is over-expressed in Down syndrome, leading to amyloid β (Aβ) over-production, a major upstream pathway leading to Alzheimer disease (AD). Statins (microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors), have pleiotropic effects including […]
Study protocol of a randomised controlled group trial of client and care outcomes in the residential dementia care setting
Chenoweth, Lynn,
King, Madeleine,
Luscombe, Georgina,
Forbes, Ian,
Jeon, Yun-Hee,
Parbury, Jane Stein,
Brodaty, Henry,
Fleming, Richard,
Haas, Marion
Purpose: Literature suggests that quality of life (QOL), quality of care (QOC) and Behavioural and Psychological Symptoms of Dementia (BPSD) can be improved by relatively simple and inexpensive person-centred approaches to nursing care practices (PCC) and modifications to physical environment (PCE). Most research on this topic is observational and few randomised controlled trials have included […]
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial
Cyarto, Elizabeth V.,
Lautenschlager, Nicola T.,
Desmond, Patricia M.,
Ames, David,
Szoeke, Cassandra,
Salvado, Olivier,
Sharman, Matthew J.,
Ellis, Kathryn A.,
Phal, Pramit M.,
Masters, Colin L.,
Rowe, Christopher C.,
Martins, Ralph N.,
Cox, Kay L.
Background: Older adults free of dementia but with subjective memory complaints (SMC) or mild cognitive impairment (MCI) are considered at increased risk of cognitive decline. Vascular risk factors (VRF), including hypertension, heart disease, smoking, hypercholesterolemia and lack of physical activity (PA) have been identified as modifiable risk factors contributing to cognitive decline, and white matter […]