This database contains 384 studies, archived under the term: "Other"
Click here to filter this large number of results.
The implementation of integrated emotion-oriented care: did it actually change the attitude, skills and time spent of trained caregivers?
van der Kooij, C.,
Droes, R.,
de Lange, J.,
Ettema, T.,
Cools, H.,
van Tilburg, W.
Background: Successful implementation is a vital precondition for investigating the outcome of care innovation. This study concerned the evaluation of the implementation of integrated emotion-oriented care (IEOC) in psychogeriatric nursing home wards. The main question was whether the trained caregivers actually applied the knowledge and techniques of IEOC during their daily work.; Methods: The study […]
Magnetization transfer imaging in premanifest and manifest huntington disease: a 2-year follow-up
van den Bogaard, S. J. A.,
Dumas, E. M.,
Hart, E. P.,
Milles, J.,
Reilmann, R.,
Stout, J. C.,
Craufurd, D.,
Gibbard, C. R.,
Tabrizi, S. J.,
van Buchem, M. A.,
van der Grond, J.,
Roos, R. A. C.
Background and Purpose: MTI is a quantitative MR imaging technique that has recently demonstrated structural integrity differences between controls and patients with HD. Potentially, MTI can be used as a biomarker for monitoring disease progression. To establish the value of MTI as a biomarker, we aimed to examine the change in these measures during the […]
Effects of dementia-care mapping on residents and staff of care homes: a pragmatic cluster-randomised controlled trial
van de Ven, Geertje,
Draskovic, Irena,
Adang, Eddy M. M.,
Donders, Rogier,
Zuidema, Sytse U.,
Koopmans, Raymond T. C. M.,
Vernooij-Dassen, Myrra J. F. J.
Background: The effectiveness of dementia-care mapping (DCM) for institutionalised people with dementia has been demonstrated in an explanatory cluster-randomised controlled trial (cRCT) with two DCM researchers carrying out the DCM intervention. In order to be able to inform daily practice, we studied DCM effectiveness in a pragmatic cRCT involving a wide range of care homes […]
Detection of disease-associated α-synuclein in the cerebrospinal fluid: a feasibility study
Unterberger, Ursula,
Lachmann, Ingolf,
Voigtländer, Till,
Pirker, Walter,
Berghoff, Anna S.,
Flach, Katharina,
Wagner, Uta,
Geneste, Aline,
Perret-Liaudet, Armand,
Kovacs, Gabor G.
With the aim to evaluate the significance and reliability of detecting disease-specific α-synuclein in the cerebrospinal fluid (CSF) we developed an ELISA and bead-assay. We used a commercial antibody (5G4) that does not bind to the physiological monomeric form of α-synuclein, but is highly specific for the disease-associated forms, including high molecular weight fraction of […]
Study of the voxel-based specific regional analysis system for Alzheimer’s disease imaging sequence after magnetic resonance apparatus replacement
Tsukagoshi, Yuki,
Kanai, Yoshihiro,
Yasui, Gou,
Abe, Yuuji,
Maemura, Keisuke,
Nakazawa, Masaki,
Yamaji, Yuugo,
Mihara, Ban
In our institute, an MR apparatus, MAGNETOM VISION (Siemens) was replaced by ECHELON Vega (HITACHI). Z-score data acquired by MPRAGE (VISION) was compared with those by radio frequency-spoiled steady-state acquisition with rewinded gradient echo (RSSG) and gradient echo inversion recovery (GEIR) (ECHELON). For this study, ten normal volunteers were recruited and their data ware obtained […]
Genetic variation in galectin-3 gene associates with cognitive function at old age
Trompet, Stella,
Jukema, Wouter,
Mooijaart, Simon P.,
Ford, Ian,
Stott, David J.,
Westendorp, Rudi G.J.,
de Craen, Anton J.M.
Inflammation plays an important role in the development of cognitive decline and dementia in old age. Galectin-3 is known for its role in acute and chronic inflammation. We assessed whether genetic variation in the LGALS3 gene, encoding for galectin-3, associates with cognitive function in the 5804 participants of the PROspective Study of Pravastatin in the […]