This database contains 291 studies, archived under the term: "Behaviour"
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A randomized controlled trial to examine the effectiveness of case management model for community dwelling older persons with mild dementia in Hong Kong
Lam, Linda C. W.,
Lee, Jenny S. W.,
Chung, Jenny C. C.,
Lau, Anna,
Woo, Jean,
Kwok, Timothy C. Y.
Objective: To evaluate a case management (CM) model for people with mild dementia, whereby resources within the family and in the community were mobilized and optimally used.; Method: Community dwelling psychiatric and geriatrics outpatients with mild dementia were randomized to receive CM by a trained occupational therapist for 4 months (CM group, N = 59) […]
Language-enriched exercise plus socialization for older adults with dementia: translation to rural communities
Felten, Kristen,
Duschene, Kathie,
MacFarlane, Dana,
Price, Susan,
Zimmerman, Suanne,
Hafez, Stephanie,
La Rue, Asenath
Interventions that stimulate and engage individuals with dementia physically, cognitively, and socially offer promise for improving health and well-being and for potentially slowing functional losses with disease progression. We describe a volunteer-based intervention that combines physical exercise, cognitive-linguistic stimulation, and social outings for older persons living with dementia in rural communities. One-year follow-up data, although […]
Effectiveness of online cognitive behavioral therapy on family caregivers of people with dementia
Kwok, Timothy,
Au, Alma,
Wong, Bel,
Ip, Isaac,
Mak, Vivian,
Ho, Florence
Purpose: Family caregivers of persons with dementia (PWD) may receive caregiver training because of logistical constraints and privacy concerns. This study evaluated the effectiveness of an online intervention for family caregivers of PWD in improving their self-efficacy in managing behavioral and psychological symptoms of dementia (BPSD), and their emotion well-being.; Subjects and Methods: A total […]
Elder-Clowning in Long-Term Dementia Care: Results of a Pilot Study
Kontos, Pia,
Miller, Karen-Lee,
Colobong, Romeo,
Palma Lazgare, Luis I.,
Binns, Malcolm,
Low, Lee-Fay,
Surr, Claire,
Naglie, Gary
OBJECTIVES: To assess the effects of elder-clowning on moderate to severe behavioral and psychological symptoms of dementia (BPSD) in nursing home residents with dementia, primarily of the Alzheimer’s type. DESIGN: Before-and-after study. SETTING: Nursing home. PARTICIPANTS: Nursing home residents with moderate to severe BPSD, as defined according to a Neuropsychiatric Inventory-Nursing Home version (NPI-NH) score […]
Phase II crossover trial of varenicline in mild-to-moderate Alzheimer’s disease
Kim, Seong Yoon,
Choi, Seong Hye,
Rollema, Hans,
Schwam, Elias M.,
McRae, Tom,
Dubrava, Sarah,
Jacobsen, Janice
Background: Evidence supports a role of α4β2 receptors in Alzheimer’s disease (AD).; Methods: This Korean, multicenter, double-blind, two-period (6 weeks each), crossover study randomized participants to the order in which they received varenicline (1 mg twice daily) and placebo. Assessments included AD Assessment Scale-Cognitive Subscale (ADAS-Cog) 75, Neuropsychiatric Inventory (NPI), adverse events (AEs) and Columbia-Suicide […]
Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil
Kano, Osamu,
Ito, Hirono,
Takazawa, Takanori,
Kawase, Yuji,
Murata, Kiyoko,
Iwamoto, Konosuke,
Nagaoka, Tetsuro,
Hirayama, Takehisa,
Miura, Ken,
Nagata, Riya,
Kiyozuka, Tetsuhito,
Aoyagi, Jo,
Sato, Ryuta,
Eguchi, Teruo,
Ikeda, Ken,
Iwasaki, Yasuo
Clinical trials have shown the benefits of acetylcholinesterase inhibitors, such as donepezil and galantamine, and an N-methyl-d-aspartate receptor antagonist, memantine, in patients with Alzheimer’s disease (AD). However, little is known regarding the effects of switching from donepezil 5 mg/day to galantamine 16 or 24 mg/day, or regarding the effects of adding memantine to established therapy […]
An integrated dementia intervention for Korean older adults
Kang, Hee-Young,
Bae, Yeong-Suk,
Kim, Eun-Hee,
Lee, Kap-Soon,
Chae, Myeong-Jeong,
Ju, Ree-Aie
Called dotage in Korea, dementia is primarily characterized by cognitive impairments. Secondary manifestations include mental- emotional problems, including depression. This study was designed to examine the effects of an integrated dementia intervention for Korean older adults. The intervention is composed of cognitive stimulation training, exercise, music, art, and horticultural therapy. Participants included 38 older adults […]
The effects of oxytocin on social cognition and behaviour in frontotemporal dementia
Jesso, S.,
Morlog, D.,
Ross, S.,
Pell, M. D.,
Pasternak, S. H.,
Mitchell, D. G. V.,
Kertesz, A.,
Finger, E. C.
Patients with behavioural variant frontotemporal dementia demonstrate abnormalities in behaviour and social cognition, including deficits in emotion recognition. Recent studies suggest that the neuropeptide oxytocin is an important mediator of social behaviour, enhancing prosocial behaviours and some aspects of emotion recognition across species. The objective of this study was to assess the effects of a […]