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Postoperative medical complications associated with anesthesia in older adults with dementia


Seitz, Dallas P., Gill, Sudeep S., Bell, Chaim M., Austin, Peter C., Gruneir, Andrea, Anderson, Geoff M., Rochon, Paula A.


Journal Of The American Geriatrics Society, Volume: 62, No.: 11, Pages.: 2102-2109

Year of Publication



Objectives: To examine the association between anesthetic technique and postoperative complications in older adults with dementia undergoing hip fracture surgery.; Design: Population-based, retrospective cohort study.; Setting: Ontario, Canada.; Participants: All older adults with dementia who underwent surgery for hip fracture repair in Ontario, Canada, between April 1, 2003 and March 31, 2011.; Measurements: The baseline characteristics of individuals who received general anesthesia (GA) and regional anesthesia (RA) were compared. Individuals who received GA were matched to similar individuals who received RA using propensity scores to control for confounding, and their outcomes compared, including 30-day mortality, intensive care unit (ICU) admissions, specific postoperative medical complications, and hospital length of stay (LOS).; Results: In the 6,135 matched pairs, there was no statistically significant difference in postoperative 30-day mortality (GA, 11.3%; RA, 10.8%, P = .44). There were no statistically significant differences in the rates of specific postoperative medical complications or LOS in the two anesthetic groups, but GA was associated with higher rates of ICU admissions (6.1% vs 4.2%, P < .001).; Conclusion: For older adults with dementia undergoing hip fracture surgery, GA and RA are associated with similar rates of most perioperative adverse events. Further studies are required to determine the optimal methods of providing anesthesia and perioperative care for older adults with dementia undergoing surgical procedures.; © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.

Bibtex Citation

@article{Seitz_2014, doi = {10.1111/jgs.13106}, url = {}, year = 2014, month = {nov}, publisher = {Wiley-Blackwell}, volume = {62}, number = {11}, pages = {2102--2109}, author = {Dallas P. Seitz and Sudeep S. Gill and Chaim M. Bell and Peter C. Austin and Andrea Gruneir and Geoff M. Anderson and Paula A. Rochon}, title = {Postoperative Medical Complications Associated with Anesthesia in Older Adults with Dementia}, journal = {Journal of the American Geriatrics Society} }


adverse, adverse effects, aged, aged, 80 and over, alzheimer disease, alzheimer’s disease, anaesthesia, and, anesthesia, anesthesia conduction, anesthesia general, cohort studies, comorbidity, complications, dementia, etiology, events, female, general, hip fracture, hip fractures, humans, intensive care units, length of stay, long term care, male, mortality, ontario, patient admission, postoperative complications, propensity score, regional, statistics & numerical data, surgery, survival analysis

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Cohort Study

Type of Outcomes

Carer Burden (instruments measuring burden), Other, Service use or cost reductions (incl. hospital use reduction, care home admission delay)


Hospital Inpatient Care

Type of Interventions

Risk Factor Modification

Risk Factor Modifications

At risk population