This database contains 162 studies, archived under the term: "Community"
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English longitudinal study of aging: Can Internet/E-mail use reduce cognitive decline?
Xavier, A. J.,
d'Orsi, E.,
de Oliveira, C. M.,
Orrell, M.,
Demakakos, P.,
Biddulph, J. P.,
Marmot, M. G.
Background: Cognitive decline is a major risk factor for disability, dementia, and death. The use of Internet/E-mail, also known as digital literacy, might decrease dementia incidence among the older population. The aim was to investigate whether digital literacy might be associated with decreased cognitive decline in older adulthood. Methods: Data from the English Longitudinal Study […]
Walking stabilizes cognitive functioning in Alzheimer’s disease (AD) across one year
Winchester, J.,
Dick, M.B.,
Gillen, D.,
Reed, B.,
Miller, B.,
Tinklenberg, J.,
Mungas, D.,
Chui, H.,
Galasko, D.,
Hewett, L.,
Cotman, C.W.
AD is a public health epidemic, which seriously impacts cognition, mood and daily activities; however, one type of activity, exercise, has been shown to alter these states. Accordingly, we sought to investigate the relationship between exercise and mood, in early-stage AD patients (N=104) from California, over a 1-year period. Patients completed the Mini-Mental State Examination […]
Mindfulness-based stress reduction for family caregivers: a randomized controlled trial
Whitebird, R. R.,
Kreitzer, M.,
Crain, A. L.,
Lewis, B. A.,
Hanson, L. R.,
Enstad, C. J.
Purpose: Caring for a family member with dementia is associated with chronic stress, which can have significant deleterious effects on caregivers. The purpose of the Balance Study was to compare a mindfulness-based stress reduction (MBSR) intervention to a community caregiver education and support (CCES) intervention for family caregivers of people with dementia.; Design and Methods: […]
Midlife cardiovascular risk factors and late cognitive impairment
Virta, Jyri J.,
Heikkilä, Kauko,
Perola, Markus,
Koskenvuo, Markku,
Räihä, Ismo,
Rinne, Juha O.,
Kaprio, Jaakko
Cardiovascular risk factors increase the risk of dementia in later life. The aims of the current study were to assess the effect of multiple midlife cardiovascular risk factors on the risk of cognitive impairment in later life, and to assess the validity of the previously suggested CAIDE Study risk score predicting dementia risk 20 years later. […]
A follow‐up intervention in severely demented patients after discharge from a special Alzheimer acute care unit: Impact on early emergency room re‐hospitalization rate
Villars, Hélène,
Dupuy, Charlotte,
Soler, Pauline,
Gardette, Virginie,
Soto, Maria E.,
Gillette, Sophie,
Nourhashemi, Fati,
Vellas, Bruno
Background: Emergency room (ER) re-hospitalizations are prevalent in severe Alzheimer’s disease affected older patients. Design: Quasi-experimental before and after study. Setting: Discharge of severely demented patients from a Special Alzheimer Acute Care Unit. Participants: A total of 390 patients hospitalized in the unit from 2007 through 2009, with at least one of the following characteristics: […]
Physical activity attenuates age-related biomarker alterations in preclinical AD
Okonkwo, O. C.,
Schultz, S. A.,
Oh, J. M.,
Larson, J.,
Edwards, D.,
Cook, D.,
Koscik, R.,
Gallagher, C. L.,
Dowling, N. M.,
Carlsson, C. M.,
Bendlin, B. B.,
LaRue, A.,
Rowley, H. A.,
Christian, B. T.,
Asthana, S.,
Hermann, B. P.,
Johnson, S. C.,
Sager, M. A.
Objective: To examine whether engagement in physical activity might favorably alter the agedependent evolution of Alzheimer disease (AD)-related brain and cognitive changes in a cohort of at-risk, late-middle-aged adults. Methods: Three hundred seventeen enrollees in the Wisconsin Registry for Alzheimer’s Prevention underwent T1 MRI; a subset also underwent ¹¹C-Pittsburgh compound B–PET (n = 186) and […]
Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer’s disease (GuidAge): a randomised placebo-controlled trial
Vellas, Bruno,
Coley, Nicola,
Ousset, Pierre-Jean,
Berrut, Gilles,
Dartigues, Jean-François,
Dubois, Bruno,
Grandjean, Hélène,
Pasquier, Florence,
Piette, François,
Robert, Philippe,
Touchon, Jacques,
Garnier, Philippe,
Mathiex-Fortunet, Hélène,
Andrieu, Sandrine
Background: Prevention strategies are urgently needed to tackle the growing burden of Alzheimer’s disease. We aimed to assess efficacy of long-term use of standardised ginkgo biloba extract for the reduction of incidence of Alzheimer’s disease in elderly adults with memory complaints.; Methods: In the randomised, parallel-group, double-blind, placebo-controlled GuidAge clinical trial, we enrolled adults aged […]