Cohen-Mansfield, Jiska, Marx, Marcia S., Freedman, Laurence S., Murad, Havi, Regier, Natalie G., Thein, Khin, Dakheel-Ali, Maha

Background: Engagement refers to the act of being occupied or involved with an external stimulus. In dementia, engagement is the antithesis of apathy. Objective: The Comprehensive Process Model of Engagement was examined, in which environmental, personal, and stimulus characteristics impact the level of engagement. Methods: Participants were 193 residents of 7 Maryland nursing with a […]

Claxton, Amy, Baker, Laura D., Hanson, Angela, Trittschuh, Emily H., Cholerton, Brenna, Morgan, Amy, Callaghan, Maureen, Arbuckle, Matthew, Behl, Colin, Craft, Suzanne

[Correction Notice: An Erratum for this article was reported in Vol 45(4) of Journal of Alzheimer’s Disease (see record [rid]2015-17286-023[/rid]). In the original article, Tables 1 and 2 were missing. Tables 1 and 2 are present in the erratum.] Previous trials have shown promising effects of intranasally administered insulin for adults with Alzheimer’s disease dementia […]

Camargos, Einstein F., Louzada, Luciana L., Quintas, Juliana L., Naves, Janeth O.S., Louzada, Fernando M., Nóbrega, Otávio T.

Objectives: There are no randomized clinical trials regarding efficacy of trazodone in the treatment of sleep disturbances (SD) in patients with Alzheimer disease (AD). We tested the efficacy and safety of trazodone to treat SD in patients with AD. Design: We conducted a double-blind, randomized and controlled trial during periods of 7–9 days at baseline […]

Belleville, Sylvie, Gauthier, Serge, Lepage, Émilie, Kergoat, Marie-Jeanne, Gilbert, Brigitte

Objective: The primary aim of this study was to identify cognitive tests that differentiate between persons with mild cognitive impairment (MCI) who later develop cognitive decline and those who remain stable. Method: This study used a prospective longitudinal design. One hundred twenty-two older adults with single-domain or multiple-domain amnestic MCI were recruited from memory clinics. […]

Banningh, Liesbeth W. A. Joosten-Weyn, Prins, Judith B., Vernooij-Dassen, Myrra J. F. J., Wijnen, Hugo H., Rikkert, Marcel G. M. Olde, Kessels, Roy P. C.

Background: Patients with mild cognitive impairment (MCI) have to deal with an uncertain prognosis and also face a multitude of memory-related problems and psychosocial consequences. A newly developed group programme proved to be feasible, however, it needed confirmation by a controlled study. Aim: This controlled study evaluates this group therapy for MCI patients aimed to […]

Alves, J., Alves-Costa, F., Magalhaes, R., Goncalves, O. F., Sampaio, A.

Although some studies point to cognitive stimulation as a beneficial therapy for older adults with cognitive impairments, this area of research and practice is still lacking dissemination and is underrepresented in many countries. Moreover, the comparative effects of different intervention durations remain to be established and, besides cognitive effects, pragmatic parameters, such as cost-effectiveness and […]

Aguiar, Paula, Monteiro, Larissa, Feres, Ana, Gomes, Irenio, Melo, Ailton

Objective: To determine the effects of rivastigmine patch associated with physical exercise versus rivastigmine patch alone in quality of life (QOL), cognition, activities of daily living (ADL) and functional mobility in Alzheimer’s disease (AD)subjects. Methods: A randomized, controlled, single-blinded trial was conducted in 40 patients with mild to moderate stages of AD. All patients were […]