This database contains 6 studies, archived under the term: "cerebrovascular disease"
Treatment of vascular risk factors is associated with slower decline in Alzheimer disease
Background: There is growing evidence that vascular risk factors (VRF) contribute to cognitive decline. Whether their treatment can slow down the progression of Alzheimer disease (AD) remains unsettled. The aim of this observational study was to evaluate whether the treatment of VRF is associated with a slower cognitive decline in patients who have AD without […]
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial
Cyarto, Elizabeth V.,
Lautenschlager, Nicola T.,
Desmond, Patricia M.,
Ames, David,
Szoeke, Cassandra,
Salvado, Olivier,
Sharman, Matthew J.,
Ellis, Kathryn A.,
Phal, Pramit M.,
Masters, Colin L.,
Rowe, Christopher C.,
Martins, Ralph N.,
Cox, Kay L.
Background: Older adults free of dementia but with subjective memory complaints (SMC) or mild cognitive impairment (MCI) are considered at increased risk of cognitive decline. Vascular risk factors (VRF), including hypertension, heart disease, smoking, hypercholesterolemia and lack of physical activity (PA) have been identified as modifiable risk factors contributing to cognitive decline, and white matter […]
Treatment with galantamine and time to nursing home placement in Alzheimer’s disease patients with and without cerebrovascular disease
Feldman, Howard H.,
Pirttila, Tuula,
Dartigues, Jean-François,
Everitt, Brian,
Van Baelen, Bart,
Schwalen, Susanne,
Kavanagh, Shane
Objective: This study evaluated patient and treatment (galantamine and other acetylcholinesterase inhibitors (AChEIs)) factors associated with the time until nursing home placement (NHP) in patients with Alzheimer’s disease (AD) with and without cerebrovascular disease (CVD).; Methods: Re-contact follow-up study conducted in 2004 of 548 patients who had previously participated in RCTs with galantamine. Time to […]