Berr, Claudine, Portet, Florence, Carrière, Isabelle, Akbaraly, Tasnime N., Feart, Catherine, Gourlet, Véronique, Combe, Nicole, Barberger-Gateau, Pascale, Ritchie, Karen

Background: Olive oil is a major component of the Mediterranean diet suggested to be beneficial to counteract Alzheimer’s disease.; Aim Of the Study: Our objective was to examine the association between olive oil use, cognitive deficit and cognitive decline in a large elderly population.; Methods: We followed 6,947 subjects with a brief baseline food frequency […]

Beking, Kristopher, Vieira, Amandio

Objective: Dietary flavonoids and their metabolites may have neuroprotective effects against age-associated neurodegenerative disorders such as Alzheimer’s and related dementias (dementia). There is a lack of population studies, however, on correlations between flavonoid intake and dementia. The main objective of the present study was to analyse such a relationship at a large-scale population level.; Design: […]

Begum, Aysha, Tsopelas, Christos, Lindesay, James, Stewart, Robert

Objective: Vascular disorders are important potential causes of cognitive impairment and common mental disorders but their specificity as risk factors has yet to be clarified. The objectives of this analysis were to compare vascular and non-vascular health problems with respect to their associations with cognitive function and common mental disorder.; Method: An analysis was carried […]

Annweiler, C., Rolland, Y., Schott, A.M., Blain, H., Vellas, B., Beauchet, O.

Background: Hypovitaminosis D has been cross-sectionally associated with dementia and stroke. The objective of this longitudinal study was to determine whether serum vitamin D deficiency at baseline could predict the onset of non-Alzheimer dementias (NAD) within 7 years among older women.; Methods: Forty high-functioning older women (78.4 years, 76.4/82.0; median, 25th/75th percentile) from the EPIDOS […]

Anderson-Hanley, Cay, Arciero, Paul J., Brickman, Adam M., Nimon, Joseph P., Okuma, Naoko, Westen, Sarah C., Merz, Molly E., Pence, Brandt D., Woods, Jeffrey A., Kramer, Arthur F., Zimmerman, Earl A.

Background: Dementia cases may reach 100 million by 2050. Interventions are sought to curb or prevent cognitive decline. Exercise yields cognitive benefits, but few older adults exercise. Virtual reality-enhanced exercise or “exergames” may elicit greater participation.; Purpose: To test the following hypotheses: (1) stationary cycling with virtual reality tours (“cybercycle”) will enhance executive function and […]

Ancelin, Marie-Laure, Carrière, Isabelle, Barberger-Gateau, Pascale, Auriacombe, Sophie, Rouaud, Olivier, Fourlanos, Spiros, Berr, Claudine, Dupuy, Anne-Marie, Ritchie, Karen

The aim of this prospective cohort study was to evaluate the effects of lipid lowering agent (LLA) intake on cognitive function in 6,830 community-dwelling elderly persons. Cognitive performance (global cognitive functioning, visual memory, verbal fluency, psychomotor speed, and executive function), clinical diagnosis of dementia, and fibrate and statin use, were evaluated at baseline, and 2, […]