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Perseverative errors on the Wisconsin Card Sorting Test and brain perfusion imaging in mild Alzheimer’s disease
Terada, Seishi,
Sato, Shuhei,
Honda, Hajime,
Kishimoto, Yuki,
Takeda, Naoya,
Oshima, Etsuko,
Yokota, Osamu,
Uchitomi, Yosuke
Background: The Wisconsin Card Sorting Test (WCST) has long been used to investigate deficits in executive function in humans. The majority of studies investigating deficient WCST performance focused on the number of categories achieved (CA) and the number of perseverative errors of the Nelson type (PEN). However, there is insufficient evidence that these two measures […]
Decision-making and outcomes of feeding tube insertion: a five-state study
Teno, Joan M.,
Mitchell, Susan L.,
Kuo, Sylvia K.,
Gozalo, Pedro L.,
Rhodes, Ramona L.,
Lima, Julie C.,
Mor, Vincent
Objectives: To examine family member’s perceptions of decision-making and outcomes of feeding tubes.; Design: Mortality follow-back survey. Sample weights were used to account for oversampling and survey design. A multivariate model examined the association between feeding tube use and overall quality of care rating regarding the last week of life.; Setting: Nursing homes, hospitals, and […]
Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study
Teipel, Stefan J.,
Reuter, Sigrid,
Stieltjes, Bram,
Acosta-Cabronero, Julio,
Ernemann, Ulrike,
Fellgiebel, Andreas,
Filippi, Massimo,
Frisoni, Giovanni,
Hentschel, Frank,
Jessen, Frank,
Klöppel, Stefan,
Meindl, Thomas,
Pouwels, Petra J.W.,
Hauenstein, Karl-Heinz,
Hampel, Harald
Diffusion tensor imaging (DTI) detects white matter damage in neuro-psychiatric disorders, but data on reliability of DTI measures across more than two scanners are still missing. In this study we assessed multicenter reproducibility of DTI acquisitions based on a physical phantom as well as brain scans across 16 scanners. In addition, we performed DTI scans […]
Quality of life of nursing‐home residents with dementia subject to surveillance technology versus physical restraints: An explorative study
te Boekhorst, S.,
Depla, M. F. I. A.,
Francke, A. L.,
Twisk, J. W. R.,
Zwijsen, S. A.,
Hertogh, C. M. P. M.
Objective: As physical restraints should only be used in exceptional cases, there is an urgent need for alternatives to restraint use. Surveillance technology could be such an alternative. This study explored whether nursing-home residents with dementia subjected to surveillance technology had better quality of life scores for mood, behavioral and societal dimensions than residents with […]
Differential perceptions of quality of life (QoL) in community-dwelling persons with mild-to-moderate dementia
Tay, Laura,
Chua, Kia Chong,
Chan, Mark,
Lim, Wee Shiong,
Ang, Yue Ying,
Koh, Evonne,
Chong, Mei Sian
Background: Discordance between patient- and caregiver-reported quality of life (QoL) is well recognized. This study sought to (i) identify predictors of discrepancy between patient- and caregiver-rated QoL amongst community-dwelling persons with mild-to-moderate dementia, and (ii) differentiate between patients who systematically rate their QoL lower versus those who rate their QoL higher relative to their caregiver […]
Infection hospitalization increases risk of dementia in the elderly
Tate, Judith A.,
Snitz, Beth E.,
Alvarez, Karina A.,
Nahin, Richard L.,
Weissfeld, Lisa A.,
Lopez, Oscar,
Angus, Derek C.,
Shah, Faraaz,
Ives, Diane G.,
Fitzpatrick, Annette L.,
Williamson, Jeffrey D.,
Arnold, Alice M.,
DeKosky, Steven T.,
Yende, Sachin
Objectives: Severe infections, often requiring ICU admission, have been associated with persistent cognitive dysfunction. Less severe infections are more common and whether they are associated with an increased risk of dementia is unclear. We determined the association of pneumonia hospitalization with risk of dementia in well-functioning older adults.; Design: Secondary analysis of a randomized multicenter […]
Impaired glucose metabolism slows executive function independent of cerebral ischemic lesions in Japanese elderly: the Takahata study
Takahashi, Yoshimi,
Iseki, Chifumi,
Wada, Manabu,
Momma, Tadasuke,
Ueki, Masao,
Kawanami, Toru,
Daimon, Makoto,
Suzuki, Kyoko,
Tamiya, Gen,
Kato, Takeo
Objective: Age is known to influence the risk of both cerebral ischemic lesions and impaired cognitive function. Diabetes mellitus (DM) can also be associated with cognitive impairment. However, there has been no study of neuropsychological performance in association with glucose metabolism status and cerebral ischemic lesions in same-aged, community-dwelling elderly persons. The present study was […]