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Memantine versus donepezil in mild to moderate Alzheimer’s disease: a randomized trial with magnetic resonance spectroscopy
Modrego, P. J.,
Fayed, N.,
Errea, J. M.,
Rios, C.,
Pina, M. A.,
Sarasa, M.
Background and Purpose: To compare memantine with the most prescribed cholinesterase inhibitor (donepezil) from a clinical viewpoint when administered in early phases of Alzheimer disease (AD), and to...
Cost-effectiveness of one year dementia follow-up care by memory clinics or general practitioners: economic evaluation of a randomised controlled trial
Meeuwsen, Els,
Melis, René,
van der Aa, Geert,
Golüke-Willemse, Gertie,
de Leest, Benoit,
van Raak, Frank,
Schölzel-Dorenbos, Carla,
Verheijen, Desiree,
Verhey, Frans,
Visser, Marieke,
Wolfs, Claire,
Adang, Eddy,
Olde Rikkert, Marcel
Objective: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners’ care.; Methods: A multicentre randomised trial with 175...
Utilisation of atypical antipsychotic drugs in institutionalised elderly persons and prevalence of metabolic alterations
Martínez Romero, G.,
Peris Martí, J.F.,
Gomar Fayos, J.,
Navarro Gosalbez, M.,
Quintana Vargas, I.,
Muelas Tirado, J.
Objectives: Describe and evaluate atypical antipsychotics utilisation on the institutionalized elderly population of the Valencian Community and prevalence of associated metabolic alterations.; Material and Methods: Multicentre transversal descriptive...
Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women’s Health Initiative randomized trials
Manson, JoAnn E.,
Chlebowski, Rowan T.,
Stefanick, Marcia L.,
Aragaki, Aaron K.,
Rossouw, Jacques E.,
Prentice, Ross L.,
Anderson, Garnet,
Howard, Barbara V.,
Thomson, Cynthia A.,
LaCroix, Andrea Z.,
Wactawski-Wende, Jean,
Jackson, Rebecca D.,
Limacher, Marian,
Margolis, Karen L.,
Wassertheil-Smoller, Sylvia,
Beresford, Shirley A.,
Cauley, Jane A.,
Eaton, Charles B.,
Gass, Margery,
Hsia, Judith,
Johnson, Karen C.,
Kooperberg, Charles,
Kuller, Lewis H.,
Lewis, Cora E.,
Liu, Simin,
Martin, Lisa W.,
Ockene, Judith K.,
O’Sullivan, Mary Jo,
Powell, Lynda H.,
Simon, Michael S.,
Van Horn, Linda,
Vitolins, Mara Z.,
Wallace, Robert B.
Importance: Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention.; Objective: To report a comprehensive, integrated overview of...
Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool
Liu, Yawu,
Mattila, Jussi,
Ruiz, Miguel Ángel Muñoz,
Paajanen, Teemu,
Koikkalainen, Juha,
van Gils, Mark,
Herukka, Sanna-Kaisa,
Waldemar, Gunhild,
Lötjönen, Jyrki,
Soininen, Hilkka
Purpose: To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations...
Risk of cerebrovascular accident associated with use of antipsychotics: population-based case-control study
Laredo, Leonor,
Vargas, Emilio,
Blasco, Antonio Javier,
Aguilar, Maria Dolores,
Moreno, Alfonso,
Portolés, Antonio
Objectives: To explore the association between use of antipsychotics and risk of cerebrovascular accident (CVA) in individuals with dementia aged 65 and older.; Design: Population-based case-control study.; Setting:...