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Fetal striatal grafting slows motor and cognitive decline of Huntington’s disease
Paganini, M.,
Biggeri, A.,
Romoli, A. M.,
Mechi, C.,
Ghelli, E.,
Berti, V.,
Pradella, S.,
Bucciantini, S.,
Catelan, D.,
Saccardi, R.,
Lombardini, L.,
Mascalchi, M.,
Massacesi, L.,
Porfirio, B.,
Di Lorenzo, N.,
Vannelli, G. B.,
Gallina, P.
...years. Adjusted post-transplantation motor score deterioration rate was reduced compared to the pretransplantation period, and to that of not-transplanted patients by 0.9 unit/years (95% CI 0.2 to 1.6). Cognitive score...
Effects of problem solving therapy on mental health outcomes in family caregivers of persons with a new diagnosis of mild cognitive impairment or early dementia: A randomized controlled trial
Garand, Linda,
Rinaldo, Donna E.,
Alberth, Mary M.,
Delany, Jill,
Beasock, Stacey L.,
Lopez, Oscar L.,
Reynolds, Charles F.,
Dew, Mary Amanda
...new cognitive diagnosis. Relative to nutritional education, PST led to significantly reduced depression symptoms, particularly among early dementia caregivers. PST also lowered caregivers’ anxiety levels, and led to lessening of...
Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial
Livingston, G.,
Barber, J.,
Rapaport, P.,
Knapp, M.,
Griffin, M.,
King, D.,
Livingston, D.,
Mummery, C.,
Walker, Z.,
Hoe, J.,
Sampson, E. L.,
Cooper, C.
...towards reduced case level anxiety (0.30, 0.08 to 1.05). Carers’ quality of life was higher in the intervention group (difference in means 4.09, 95% confidence interval 0.34 to 7.83) but...
Time until incident dementia among Medicare beneficiaries using centrally acting or non-centrally acting ACE inhibitors
Hebert, Paul L.,
McBean, Alexander Marshall,
O'Connor, Heidi,
Frank, Barbara,
Good, Charles,
Maciejewski, Matthew L.
...is associated with a reduced incidence of Alzheimer’s disease and related dementias (ADRD).; Objective: The aim of this research was to assess the effect of CA versus non-CA ACEI use...