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This database contains 1433 studies, archived under the term: ""

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Integrative cognitive-behavioral and spiritual counseling for rural dementia caregivers with depression

Objective: Discuss initial evaluation of a program for training faith community nurses (FCNs) to conduct cognitive-behavioral and spiritual counseling (CBSC) for rural dementia caregivers (CGs), and present 2 case studies on the use of CBSC for treating depression in this population.; Study Design: Pre-post evaluation of the effectiveness of CBSC training and a case study […]

A biobehavioral home-based intervention and the well-being of patients with dementia and their caregivers: the COPE randomized trial

Context: Optimal treatment to postpone functional decline in patients with dementia is not established.; Objective: To test a nonpharmacologic intervention realigning environmental demands with patient capabilities.; Design, Setting, and Participants: Prospective 2-group randomized trial (Care of Persons with Dementia in their Environments [COPE]) involving patients with dementia and family caregivers (community-living dyads) recruited from March […]

A non-pharmacologic approach to address challenging behaviors of Veterans with dementia: description of the tailored activity program-VA randomized trial

Background: Behavioral symptoms accompanying dementia are associated with increased health care costs, reduced quality of life and daily functioning, heightened family caregiver burden, and nursing home placement. Standard care typically involves pharmacologic agents, but these are, at best, modestly effective, carry serious risks, including mortality, and do not address behavioral symptoms families consider most distressful […]

Using the Montessori approach for a clientele with cognitive impairments: A quasi-experimental study design

Background: The choice of activities responding to the needs of people with moderate to severe dementia is a growing concern for care providers trying to target the need for a feeling of self-accomplishment by adapting activities to the abilities of elderly patients. The activities created by Maria Montessori seem to be adaptable to this clientele. […]

A prospective field study for sensor-based identification of fall risk in older people with dementia

Objective: Aim of this study was to make a fall prognosis in a cohort of older people with dementia in short-term (2 month), mid-term (4 month) and long-term (8 month) intervals using accelerometry during the subjects’ everyday life. Methods: The study was designed as a longitudinal cohort study. The subjects were recruited from a nursing […]

Web-based psychosocial assessment for caregivers of persons with dementia: a feasibility study

Purpose and Design: Most of the 5.4 million Americans with dementia are cared for by family members who experience care needs and time constraints. This quasi-experimental study examined the experience of using a psychosocial assessment instrument to understand caregiver needs delivered in an interview versus a self-administered web-based format.; Methods: Ten family caregivers were randomized […]

Japanese-English language equivalence of the Cognitive Abilities Screening Instrument among Japanese-Americans

Background: The Cognitive Abilities Screening Instrument (CASI) was designed for use in cross-cultural studies of Japanese and Japanese-American elderly in Japan and the U.S.A. The measurement equivalence in Japanese and English had not been confirmed in prior studies.; Methods: We analyzed the 40 CASI items for differential item functioning (DIF) related to test language, as […]

Cost effectiveness of donepezil in the treatment of mild to moderate Alzheimer’s disease: A UK evaluation using discrete-event simulation

Background: Recommendations in the UK suggest restricting treatment of Alzheimer’s disease with cholinesterase inhibitors, on cost-effectiveness grounds, to patients with moderate cognitive decline. As the economic analyses that informed these recommendations have been the subject of debate, we sought to address the potential limitations of existing models and produce estimates of donepezil treatment cost effectiveness […]

Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease

Objective: To determine whether oral quinacrine increases survival in sporadic Creutzfeldt-Jakob disease (sCJD).; Methods: This NIH/National Institute on Aging-funded, double-blinded, placebo-controlled, stratified randomization treatment trial was conducted at the University of California, San Francisco from February 2005 through May 2009 (ClinicalTrials.gov, NCT00183092). Subjects were randomized (50:50) to quinacrine (300 mg daily) or placebo with inpatient […]

Intergenerational volunteering and quality of life for persons with mild to moderate dementia: results from a 5-month intervention study in the United States

Objectives: To evaluate whether a structured intergenerational volunteering intervention would enhance quality of life (QOL) for persons with mild to moderate dementia.; Methods: Fifteen participants were randomized into intervention and control groups. The intervention group participated in hour-long structured volunteer sessions with a kindergarten class and an older elementary class in alternating weeks during a […]

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