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Your search has found 137 articles in the database for the term 'Physical Distress'

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Supervised exercise to reduce agitation in severely cognitively impaired persons

Background: Several studies have shown an improvement in depression, activities of daily living, and agitation in cognitively impaired subjects who undergo a long-term exercise program. These studies have...

Cognitive stimulation for Portuguese older adults with cognitive impairment: A randomized controlled trial of efficacy, comparative duration, feasibility, and experiential relevance

Although some studies point to cognitive stimulation as a beneficial therapy for older adults with cognitive impairments, this area of research and practice is still lacking dissemination and...

Results from a pilot study on amiodarone administration in monogenic frontotemporal dementia with granulin mutation

Frontotemporal dementia (FTD) is one of the most important neurodegenerative conditions and Granulin (GRN) is one of the major genes associated to the disease. FTD-GRN patients are still...

Measuring the experience and perception of suffering

...Purpose: assess psychometric properties of scales developed to assess experience and perception of physical, psychological, and existential suffering in older individuals.; Design and Methods: scales were administered to 3...

Comparison of non-vertebral fracture between minodronate and risedronate therapy in elderly female patients with Alzheimer disease

Objectives: Minodronate is a nitrogen-containing bisphosphonate that is commercially available for the treatment of osteoporosis in Japan. Preclinical studies demonstrated that minodronate is at least 10 times more...

Comparison of the effects of transdermal andoral rivastigmine on cognitive function and EEG markers in patients with Alzheimer’s disease

Background: Alzheimer’s disease (AD) is the most common cause of dementia in older patients. Rivastigmine (RV, Exelon, Novartis), a reversible cholinesterase inhibitor, improves clinical manifestations of AD and...

Evaluation of the effects of galantamine on cardiac function in elderly patients with Alzheimer’s disease

Background: Galantamine, a cholinesterase inhibitor, is used as a first-line drug in the treatment of Alzheimer’s disease (AD). However, it may have vagotonic effects, which may cause bradycardia...

Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil

Clinical trials have shown the benefits of acetylcholinesterase inhibitors, such as donepezil and galantamine, and an N-methyl-d-aspartate receptor antagonist, memantine, in patients with Alzheimer’s disease (AD). However, little...

The effectiveness of a stimulation program on cognitive capacity among individuals older than 60

...of seven home visits, including intervention conversation, newspaper/ book reading, painting/handcraft activities, and physical exercise. The Mini Mental State Test scores of the participants statistically increased, whereas the Beck Anxiety...

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