Yang, Yuan-Han, Wu, Shey-Lin, Chou, Mei-Chuan, Lai, Chiou-Lian, Chen, Su-Hwei, Liu, Ching-Kuan

Donepezil has been approved for the treatment for mild-to-moderate Alzheimer’s disease (AD), but the therapeutic response rate varies from 20 to 60%. A higher oral dosage was suggested to have a better therapeutic response in reported results, but the plasma concentration of donepezil was not examined with respect to the therapeutic outcomes in those studies. […]

Yeh, Yen-Chi, Liu, Chien-Liang, Peng, Li-Ning, Lin, Ming-Hsien, Chen, Liang-Kung

Aim: Medication-related anticholinergic burden is a quality indicator for geriatric pharmacotherapy; however, little is known regarding the benefits of reducing anticholinergic burden for demented patients; Methods: Demented residents in a Veteran Home were enrolled for this study and an educational program was held for primary care physicians providing services at the Veterans Home. Residents were […]

Lai, Shih-Wei, Liao, Kuan-Fu, Lin, Cheng-Li, Sung, Fung-Chang

This study investigated whether an association exists between irritable bowel syndrome (IBS) and the risk of Parkinson’s disease. This is a retrospective cohort study using the dataset of the Taiwan National Health Insurance Program from 2000 to 2010. We identified 23,875 patients (aged 20 years or older) with newly diagnosed IBS as the IBS group […]

Kuo, Li-Min, Huang, Huei-Ling, Huang, Hsiu-Li, Liang, Jersey, Chiu, Yi-Chen, Chen, Sien-Tsong, Kwok, Yam-Ting, Hsu, Wen-Chuin, Shyu, Yea-Ing L.

Objectives: Little is known about the longitudinal effects of training programs on family caregivers’ health-related quality of life (HRQoL) and depressive symptoms over time. Therefore, the purpose of this study was to examine the effects of a home-based caregiver training program on HRQoL and depressive symptoms for family caregivers of older persons with dementia.; Methods: […]