Dougherty, John H., Jr., Cannon, Rex L., Nicholas, Christopher R., Hall, Lorin, Hare, Felicia, Carr, Erika, Dougherty, Andrew, Janowitz, Jennifer, Arunthamakun, Justin

The computer self test (CST) is an interactive, internet-based instrument designed to assess functional cognitive domains impaired by Alzheimer’s disease (AD) and mild cognitive impairment (MCI). This study consisted of 215 total subjects with a mean age of 75.24. The 84 cognitively impaired patients (excluding patients diagnosed as MCI) met all criteria set forth by […]

Schiepers, Olga J. G., van Boxtel, Martin P. J., de Groot, Renate H. M., Jolles, Jelle, Kok, Frans J., Verhoef, Petra, Durga, Jane

Long-term supplementation with folic acid may improve cognitive performance in older individuals. The relationship between folate status and cognitive performance might be mediated by changes in methylation capacity, as methylation reactions are important for normal functioning of the brain. Although aberrant DNA methylation has been implicated in neurodevelopmental disorders, the relationship between DNA methylation status […]

de Sousa, Odete Luísa Vicente, Amaral, Teresa F.

Short-term nutritional supplements enable an improvement in Alzheimer patients’ nutritional status, but it remains to be seen whether they will be sufficient to improve long-term nutritional status. The aim of this study was to evaluate the long-term impact of a 3-week nutritional supplementation on the nutritional status of undernourished patients with probable mild Alzheimer disease. […]

Salva, A., Andrieu, S., Fernandez, E., Schiffrin, E. J., Moulin, J., Decarli, B., Rojano-i-Luque, X., Guigoz, Y., Vellas, B.

Objective: To assess the effectiveness of health and nutrition program (NutriAlz) versus usual care on functional level in elderly people with dementia living at home, as well as on clinical practice related to nutrition and on the caregiver’s burden.; Design: Cluster randomized multi-centre study with one-year follow-up.; Setting: 11 Alzheimer outpatients and day care centres […]

Salva, A., Andrieu, S., Fernandez, E., Schiffrin, E. J., Moulin, J., Decarli, B., Guigoz, Y., Vellas, B.

Background: There is a lack of data on global weight loss prevention programs for patients with dementia or clear evidence about their impact on a functional level, caregiver burden or the use of healthcare and social resources. NutriAlz is a socio-educative and nutritional intervention program to prevent weight loss and loss of function in dementia […]

Wu, Hua-Shan, Lin, Li-Chan

Aim: To examine the long-term effects of fixed/individualized spaced retrieval combined with Montessori-based activities on nutritional status and body mass index and nutritional improvement’s moderating effect on depressive symptoms for people with dementia during a specific follow-up period. Background: The decrease in food intake, often combined with poor nutrition, may induce depressive symptoms in people […]