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This database contains 135 studies, archived under the term: "severity of illness index"

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Longitudinal assessment of psychotherapeutic day hospital treatment for neuropsychiatric symptoms in dementia

Objective: Behavioral and psychological symptoms (BPSD) of dementia are associated with more rapid cognitive deterioration as well as increased caregiver stress. The effectiveness of psychiatric day hospital care for this condition remains disputed. We report here the assessment of a psychotherapeutic day hospital program in a series of elderly people with dementia and concomitant BPSD.; […]

The effect of music therapy compared with general recreational activities in reducing agitation in people with dementia: a randomised controlled trial

Objective: This study aimed to compare the effects of music therapy with general recreational day activities in reducing agitation in people with dementia, residing in nursing home facilities.; Methods: In a randomised controlled design, residents with dementia (n = 94) were allocated to either music therapy or recreational activities. Both music therapy and general activities were offered […]

The contribution of intimate live music performances to the quality of life for persons with dementia

Objective: The aim of this study was to assess the effect of intimate live music performances delivered by professional singers on the quality of life of persons with mild and severe dementia in nursing homes.; Methods: A sample of 54 persons with varying degrees of dementia participated in the study. Complete data sets are available […]

A validated risk score to estimate mortality risk in patients with dementia and pneumonia: barriers to clinical impact

Background: The clinical impact of risk score use in end-of-life settings is unknown, with reports limited to technical properties.; Methods: We conducted a mixed-methods study to evaluate clinical impact of a validated mortality risk score aimed at informing prognosis and supporting clinicians in decision-making in dementia patients with pneumonia. We performed a trial (n = […]

Effects of SolCos model-based individual reminiscence on older adults with mild to moderate dementia due to Alzheimer disease: a pilot study

Objective: To examine effects of individual thematically-based reminiscence sessions based on the SolCos model for older adults with dementia because of Alzheimer disease (AD) as a pilot study.; Background: Reminiscence activities are popular within nursing homes and generally considered to be enjoyable and helpful, however, there is a paucity of robust data demonstrating therapeutic impact. […]

Prevalence of anosognosia in Alzheimer’s disease

Background and Objective: Anosognosia is a disorder that affects the clinical presentation of Alzheimer’s disease (AD), increasing in frequency with the evolution of AD. The objective was to determine the prevalence of anosognosia and analyze the associated factors and predictors.; Patients and Method: Multicenter transversal and observational study of 345 AD patients. Anosognosia was assessed […]

Perseverative errors on the Wisconsin Card Sorting Test and brain perfusion imaging in mild Alzheimer’s disease

Background: The Wisconsin Card Sorting Test (WCST) has long been used to investigate deficits in executive function in humans. The majority of studies investigating deficient WCST performance focused on the number of categories achieved (CA) and the number of perseverative errors of the Nelson type (PEN). However, there is insufficient evidence that these two measures […]

Results of the Trail Making Test among patients suffering from depressive disorders and organic depressive disorders

Aim: Coexistence of depression and dementia for many years has been widely studied for many years. According to the authors for clinical practice, both psychiatric and psychological, it is also important to effectively differentiate between these disease entities. The aim of this study is to compare the implementation of the Trail Making Test (TMT) in […]

Physical and psychological effects of 6-week tactile massage on elderly patients with severe dementia

Tactile massage is a soft massage that improves physical relaxation and psychological well-being. The purpose of this study was to clarify the effects of a 6-week tactile massage on changes in physical and mental function, symptoms of behavioral and psychological symptoms of dementia (BPSD) among elderly patients with dementia. In addition, chromogranin A (CgA) levels […]

Cognitive subdomain responses to galantamine in Alzheimer’s disease

We investigated the effects of galantamine on cognitive subdomains in Alzheimer’s disease (AD). Sixty-six patients with mild-to-moderate AD received open-label galantamine for 52 weeks. Cognitive function was measured using the Korean version of the Alzheimer’s Disease Assessment Scale-cognitive subscale (ADAS-cog-K). Response to galantamine was defined as “improvement or no deterioration” on the total scores of […]

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