Babiloni, Claudio, Frisoni, Giovanni B., Del Percio, Claudio, Zanetti, Orazio, Bonomini, Cristina, Cassetta, Emanuele, Pasqualetti, Patrizio, Miniussi, Carlo, De Rosas, Mario, Valenzano, Anna, Cibelli, Giuseppe, Eusebi, Fabrizio, Rossini, Paolo M.

Objective: Non-steroidal anti-inflammatory drugs such as ibuprofen have a protective role on risk of Alzheimer’s disease (AD). Here we evaluated the hypothesis that long-term ibuprofen treatment affects cortical sources of resting electroencephalographic (EEG) rhythms in mild AD patients.; Methods: Twenty-three AD patients (13 treated AD IBUPROFEN; 10 untreated AD PLACEBO) were enrolled. Resting EEG data […]

Zhang, Yu, Tartaglia, Maria Carmela, Schuff, Norbert, Chiang, Gloria C., Ching, Christopher, Rosen, Howard J., Gorno-Tempini, Maria Luisa, Miller, Bruce L., Weiner, Michael W.

Brain magnetic resonance imaging (MRI) studies have demonstrated regional patterns of brain macrostructural atrophy and white matter microstructural alterations separately in the three major subtypes of frontotemporal lobar degeneration (FTLD), which includes behavioral variant frontotemporal dementia (bvFTD), semantic dementia (SD), and progressive nonfluent aphasia (PNFA). This study was to investigate to what extent the pattern […]

Van Puyvelde, Katrien, Mets, Tony

Aim: To record in real life the appreciation of elderly patients, their caregivers and physicians of a once daily formulation of prolonged release of galantamine in the treatment of mild to moderate Alzheimer’s disease.; Methods: A prospective, multicenter, observational study was conducted in 128 elderly patients, treated for 6 months with galantamine, donepezil or rivastigmine.; […]