Herrmann, Nathan, Gauthier, Serge, Boneva, Neli, Lemming, Ole Michael

Background: Agitation and aggression in Alzheimer’s disease (AD) are amongst the most serious of neuropsychiatric symptoms, and contribute to poor outcomes and worse quality of life. Previous studies have suggested a benefit for memantine on agitation and aggression, but none have examined its efficacy in community-dwelling patients with significant agitation and aggression at baseline, utilizing […]

Gozalo, Pedro, Prakash, Shivaani, Qato, Danya M., Sloane, Philip D., Mor, Vincent

Objectives: To evaluate the effectiveness of the Bathing Without a Battle intervention in reducing physical and verbal aggressive behaviors for nursing home residents with dementia.; Design: A randomized crossover diffusion study, with one group receiving the intervention after one round of baseline observations and a delayed intervention group receiving the intervention after two rounds of […]

Fu, Chieh-Yu, Moyle, Wendy, Cooke, Marie

Background: Aromatherapy and hand massage therapies have been reported to have some benefit for people with dementia who display behavioural symptoms; however there are a number of limitations of reported studies. The aim is to investigate the effect of aromatherapy (3% lavender oil spray) with and without hand massage on disruptive behaviour in people with […]

Freund-Levi, Yvonne, Jedenius, Erik, Tysen-Bäckström, Ann Christine, Lärksäter, Marie, Wahlund, Lars-Olof, Eriksdotter, Maria

Objective: To examine the effects of galantamine and risperidone on neuropsychiatric symptoms in dementia (NPSD) and global function.; Methods: Using a randomized, controlled and open-blind, one-center trial at an in- and outpatient clinic at a university hospital, we studied 100 adults with probable dementia and NPSD. Participants received galantamine (N = 50, target dose 24 mg) […]

Dunn, K. S., Riley-Doucet, C. K.

Purpose: The purpose of this study was to determine if there were any differences in the behavioral responses of persons with dementia while listening to nonreligious and religious music within a multisensory environment.; Research Design: A within-subjects, repeated measures design was used.; Method: Participants were exposed to both musical genres during multiple sessions over a […]

Delphin-Combe, Floriane, Rouch, Isabelle, Martin-Gaujard, Géraldine, Relland, Solveig, Krolak-Salmon, Pierre

An innovative non-pharmacological intervention called Voix d’Or(®) (Golden Voice) was proposed in the Cognitive behavioral unit (CBU) of the Memory center at the Hospices civils in Lyon. Voix d’Or(®) offers eight sound activities disseminated via an audio device based on different approaches sociotherapeutic (music therapy, reminiscence, relaxation, reorientation in reality). The aim of this study […]

Bédard, Annick, Landreville, Philippe, Voyer, Philippe, Verreault, René, Vézina, Jean

Objectives: Positive results have been reported with psychosocial interventions used to reduce verbal agitation (VA) in people with dementia, but there is no clear information regarding the proportion of persons who demonstrate significant behavioural improvement with such treatments. The main objectives of this pilot study are (a) to identify the proportion of persons with dementia […]

Aman, Edris, Thomas, David R.

Background: Several studies have shown an improvement in depression, activities of daily living, and agitation in cognitively impaired subjects who undergo a long-term exercise program. These studies have not considered the short-term effects of exercise.; Objectives: The purpose of this study was to investigate the short-term effects of a limited, supervised exercise program on agitation, […]