This database contains 536 studies, archived under the term: "psychology"
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Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment
Background: Differentiating amnestic mild cognitive impairment (aMCI) from normal cognition is difficult in clinical settings. Self-reported and informant-reported memory complaints occur often in both clinical groups, which then necessitates the use of a comprehensive neuropsychological examination to make a differential diagnosis. However, the ability to identify cognitive symptoms that are predictive of aMCI through informant-based […]
Efficacy and safety of the dopaminergic stabilizer Pridopidine (ACR16) in patients with Huntington’s disease
Lundin, Anders,
Dietrichs, Espen,
Haghighi, Sara,
Göller, Marie-Louise,
Heiberg, Arvid,
Loutfi, Ghada,
Widner, Håkan,
Wiktorin, Klas,
Wiklund, Leif,
Svenningsson, Anders,
Sonesson, Clas,
Waters, Nicholas,
Waters, Susanna,
Tedroff, Joakim
Objectives: To evaluate the efficacy and safety of the dopaminergic stabilizer pridopidine (ACR16) in patients with Huntington’s disease (HD).; Methods: In a randomized, double-blind, placebo-controlled, 4-week trial, patients with HD received pridopidine (50 mg/d, n = 28) or placebo (n = 30). The primary outcome measure was the change from baseline in weighted cognitive score, […]
Maintenance of health and relief for caregivers of elderly with dementia by using “initial case management”: experiences from the Lighthouse Project on Dementia, Ulm, ULTDEM-study
Lukas, A.,
Kilian, R.,
Hay, B.,
Muche, R.,
von Arnim, C.A.F.,
Otto, M.,
Riepe, M.,
Jamour, M.,
Denkinger, M.D.,
Nikolaus, T.
Background: When facing the well-known demographic development with an increasing number of people suffering from dementia, there is a need of programmes to support nursing relatives and care at home. Many support services have been established in the past few years but they are rarely used by the relatives and the patients. The purpose of […]
Making physical activity accessible to older adults with memory loss: a feasibility study
Purpose: For individuals with mild cognitive impairment (MCI), memory loss may prevent successful engagement in exercise, a key factor in preventing additional disability. The Resources and Activities for Life Long Independence (RALLI) program uses behavioral principles to make exercise more accessible for these individuals. Exercises are broken into small steps, sequenced, and linked with cues […]
Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial
Livingston, G.,
Barber, J.,
Rapaport, P.,
Knapp, M.,
Griffin, M.,
King, D.,
Livingston, D.,
Mummery, C.,
Walker, Z.,
Hoe, J.,
Sampson, E. L.,
Cooper, C.
Objective: To assess whether a manual based coping strategy compared with treatment as usual reduces depression and anxiety symptoms in carers of family members with dementia.; Design: Randomised, parallel group, superiority trial.; Setting: Three mental health community services and one neurological outpatient dementia service in London and Essex, UK.; Participants: 260 carers of family members […]
More insight into the concept of apathy: a multidisciplinary depression management program has different effects on depressive symptoms and apathy in nursing homes
Leontjevas, Ruslan,
Teerenstra, Steven,
Smalbrugge, Martin,
Vernooij-Dassen, Myrra J. F. J.,
Bohlmeijer, Ernst T.,
Gerritsen, Debby L,
Koopmans, Raymond T. C. M.
Background: Apathy is common in nursing home (NH) residents and it overlaps with depression. This study examines the effects of a multidisciplinary depression program on apathy and depressive motivational and mood symptoms.; Methods: Secondary analyses of a stepped-wedge cluster-randomized controlled trial were conducted with six measurements. Sixteen dementia NH units and 17 somatic units were […]