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This database contains 366 studies, archived under the term: "methods"

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Effects of a psychological intervention in a primary health care center for caregivers of dependent relatives: a randomized trial
Purpose: To assess, in the context of Primary Health Care (PHC), the effect of a psychological intervention in mental health among caregivers (CGs) of dependent relatives.; Design and Methods: Randomized multicenter, controlled clinical trial. The 125 CGs included in the trial were receiving health care in PHC.; Inclusion Criteria: Identifying oneself as principal CG of […]

A randomized controlled trial of an activity specific exercise program for individuals with Alzheimer disease in long-term care settings
Objective: To determine whether an activity specific exercise program could improve ability to perform basic mobility activities in long-term care residents with Alzheimer disease (AD).; Design: Randomized, controlled, single-blinded clinical trial.; Setting: Residents of 7 long-term care facilities.; Participants: Eighty-two long-term care residents with mild to severe AD.; Intervention: An activity specific exercise program was […]

Individual music therapy for agitation in dementia: an exploratory randomized controlled trial
Objectives: Agitation in nursing home residents with dementia leads to increase in psychotropic medication, decrease in quality of life, and to patient distress and caregiver burden. Music therapy has previously been found effective in treatment of agitation in dementia care but studies have been methodologically insufficient. The aim of this study was to examine the […]

Application of immunosignatures to the assessment of Alzheimer’s disease
Objective: Accurate assessment of Alzheimer’s disease (AD), both presymptomatically and at different disease stages, will become increasingly important with the expanding elderly population. There are a number of indications that the immune system is engaged in AD. Here we explore the ability of an antibody-profiling technology to characterize AD and screen for peptides that may […]

Screening by telephone in the Alzheimer’s disease anti-inflammatory prevention trial
Compared with in-person assessment methods, telephone screening for dementia and other cognitive syndromes may improve efficiency of large population studies or prevention trials. We used data from the Alzheimer’s Disease Anti-Inflammatory Prevention Trial to compare performance of a four-test Telephone Assessment Battery (TAB) that included the Telephone Interview for Cognitive Status (TICS) to that of […]

Efficacy of music therapy treatment based on cycles of sessions: a randomised controlled trial
We undertook a randomised controlled trial to assess whether a music therapy (MT) scheme of administration, including three working cycles of one month spaced out by one month of no treatment, is effective to reduce behavioural disturbances in severely demented patients. Sixty persons with severe dementia (30 in the experimental and 30 in the control […]

Utility of the multiple-stimulus without replacement procedure and stability of preferences of older adults with dementia
Paired-stimulus preference assessments have been used effectively with individuals with dementia to identify stimuli to increase engagement and to minimize negative affect and problem behavior.We evaluated whether a multiple-stimulus without replacement preference assessment could be used with older adults with dementia and whether preferences remained stable over time. Seven participants completed preference assessments and confirmatory […]

Repetitive transcranial magnetic stimulation combined with cognitive training is a safe and effective modality for the treatment of Alzheimer’s disease: a randomized, double-blind study
Cortical excitability can be modulated using repetitive transcranial magnetic stimulation (rTMS). Previously, we showed that rTMS combined with cognitive training (rTMS-COG) has positive results in Alzheimer’s disease (AD). The goal of this randomized double-blind, controlled study was to examine the safety and efficacy of rTMS-COG in AD. Fifteen AD patients received 1-h daily rTMS-COG or […]

A validity study of the Working Group’s Autobiographical Memory Test for individuals with moderate to severe intellectual disability
The purpose of the present study was to investigate the validity of the Working Group’s Autobiographical Memory Test as a dementia screening tool for individuals with moderate to severe intellectual disabilities (ID). Twenty-one participants with Dementia of Alzheimer’s Type (DAT) and moderate to severe ID and 42 controls with similar levels of ID were tested. […]

Clock drawing in the Montreal Cognitive Assessment: recommendations for dementia assessment
Background: Clock drawing is part of the Montreal Cognitive Assessment (MoCA) test but may have administration and scoring limitations. We assessed (1) the reliability of the MoCA clock criteria relative to a published error scoring approach, (2) whether command-only administration could distinguish dementia from cognitively intact individuals and (3) the value of adding a clock […]

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