This database contains 366 studies, archived under the term: "methods"
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Walking stabilizes cognitive functioning in Alzheimer’s disease (AD) across one year
Winchester, J.,
Dick, M.B.,
Gillen, D.,
Reed, B.,
Miller, B.,
Tinklenberg, J.,
Mungas, D.,
Chui, H.,
Galasko, D.,
Hewett, L.,
Cotman, C.W.
AD is a public health epidemic, which seriously impacts cognition, mood and daily activities; however, one type of activity, exercise, has been shown to alter these states. Accordingly, we sought to investigate the relationship between exercise and mood, in early-stage AD patients (N=104) from California, over a 1-year period. Patients completed the Mini-Mental State Examination […]
Video-based coping skills to reduce health risk and improve psychological and physical well-being in Alzheimer’s disease family caregivers
Williams, Virginia P.,
Bishop-Fitzpatrick, Lauren,
Lane, James D.,
Gwyther, Lisa P.,
Ballard, Edna L.,
Vendittelli, Analise P.,
Hutchins, Tiffany C.,
Williams, Redford B.
Objective: To determine whether video-based coping skills (VCS) training with telephone coaching reduces psychosocial and biological markers of distress in primary caregivers of a relative with Alzheimer’s disease or related dementia (ADRD).; Methods: A controlled clinical trial was conducted with 116 ADRD caregivers who were assigned, alternately as they qualified for the study, to a […]
A feasibility study and pilot randomised trial of a tailored prevention program to reduce falls in older people with mild dementia
Wesson, Jacqueline,
Clemson, Lindy,
Brodaty, Henry,
Lord, Stephen,
Taylor, Morag,
Gitlin, Laura,
Close, Jacqueline
Background: People with dementia have a disproportionately high rate of falls and fractures and poorer outcomes, yet there is currently no evidence to guide falls prevention in this population.; Methods: A randomised trial design was used to test feasibility of study components and acceptability of a home hazard reduction and balance and strength exercise fall […]
Longitudinal assessment of psychotherapeutic day hospital treatment for neuropsychiatric symptoms in dementia
Weber, Kerstin,
Meiler-Mititelu, Corina,
Herrmann, François Robert,
Delaloye, Christophe,
Giannakopoulos, Panteleimon,
Canuto, Alessandra
Objective: Behavioral and psychological symptoms (BPSD) of dementia are associated with more rapid cognitive deterioration as well as increased caregiver stress. The effectiveness of psychiatric day hospital care for this condition remains disputed. We report here the assessment of a psychotherapeutic day hospital program in a series of elderly people with dementia and concomitant BPSD.; […]
A randomized crossover trial to study the effect of personalized, one-to-one interaction using Montessori-based activities on agitation, affect, and engagement in nursing home residents with Dementia
van der Ploeg, Eva S,
Eppingstall, Barbara,
Camp, Cameron J.,
Runci, Susannah J.,
Taffe, John,
O'Connor, Daniel W.
Background: Increasingly more attention has been paid to non-pharmacological interventions as treatment of agitated behaviors that accompany dementia. The aim of the current study is to test if personalized one-to-one interaction activities based on Montessori principles will improve agitation, affect, and engagement more than a relevant control condition.; Methods: We conducted a randomized crossover trial […]
Magnetization transfer imaging in premanifest and manifest huntington disease: a 2-year follow-up
van den Bogaard, S. J. A.,
Dumas, E. M.,
Hart, E. P.,
Milles, J.,
Reilmann, R.,
Stout, J. C.,
Craufurd, D.,
Gibbard, C. R.,
Tabrizi, S. J.,
van Buchem, M. A.,
van der Grond, J.,
Roos, R. A. C.
Background and Purpose: MTI is a quantitative MR imaging technique that has recently demonstrated structural integrity differences between controls and patients with HD. Potentially, MTI can be used as a biomarker for monitoring disease progression. To establish the value of MTI as a biomarker, we aimed to examine the change in these measures during the […]