This database contains 1041 studies, archived under the term: "male"
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Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer’s disease (GuidAge): a randomised placebo-controlled trial
Vellas, Bruno,
Coley, Nicola,
Ousset, Pierre-Jean,
Berrut, Gilles,
Dartigues, Jean-François,
Dubois, Bruno,
Grandjean, Hélène,
Pasquier, Florence,
Piette, François,
Robert, Philippe,
Touchon, Jacques,
Garnier, Philippe,
Mathiex-Fortunet, Hélène,
Andrieu, Sandrine
Background: Prevention strategies are urgently needed to tackle the growing burden of Alzheimer’s disease. We aimed to assess efficacy of long-term use of standardised ginkgo biloba extract for the reduction of incidence of Alzheimer’s disease in elderly adults with memory complaints.; Methods: In the randomised, parallel-group, double-blind, placebo-controlled GuidAge clinical trial, we enrolled adults aged […]
Cognitive rehabilitation changes memory-related brain activity in people with Alzheimer disease
van Paasschen, J.,
Clare, L.,
Yuen, K. S. L.,
Woods, R. T.,
Evans, S. J.,
Parkinson, C. H.,
Rugg, M. D.,
Linden, D. E. J.
Background: People with Alzheimer disease (AD) are capable of new learning when cognitive support is provided, suggesting that there is plasticity even in a degenerating brain. However, it is unclear how a cognition-focused intervention operates on a neural level.; Objective: The present study examined the effects of cognitive rehabilitation (CR) on memory-related brain activation in […]
Do nurse-led skill training interventions affect informal caregivers’ out-of-pocket expenditures?
Van Houtven, C. H.,
Thorpe, J. M.,
Chestnutt, D.,
Molloy, M.,
Boling, J. C.,
Davis, L. L.
Purpose Of the Study: This paper is a report of a study of the Assistance, Support, and Self-health Initiated through Skill Training (ASSIST) randomized control trial. The aim of this paper is to understand whether participating in ASSIST significantly changed the out-of-pocket (OOP) costs for family caregivers of Alzheimer’s disease (AD) or Parkinson’s disease (PD) […]
A randomized crossover trial to study the effect of personalized, one-to-one interaction using Montessori-based activities on agitation, affect, and engagement in nursing home residents with Dementia
van der Ploeg, Eva S,
Eppingstall, Barbara,
Camp, Cameron J.,
Runci, Susannah J.,
Taffe, John,
O'Connor, Daniel W.
Background: Increasingly more attention has been paid to non-pharmacological interventions as treatment of agitated behaviors that accompany dementia. The aim of the current study is to test if personalized one-to-one interaction activities based on Montessori principles will improve agitation, affect, and engagement more than a relevant control condition.; Methods: We conducted a randomized crossover trial […]
The implementation of integrated emotion-oriented care: did it actually change the attitude, skills and time spent of trained caregivers?
van der Kooij, C.,
Droes, R.,
de Lange, J.,
Ettema, T.,
Cools, H.,
van Tilburg, W.
Background: Successful implementation is a vital precondition for investigating the outcome of care innovation. This study concerned the evaluation of the implementation of integrated emotion-oriented care (IEOC) in psychogeriatric nursing home wards. The main question was whether the trained caregivers actually applied the knowledge and techniques of IEOC during their daily work.; Methods: The study […]
Effects of dementia-care mapping on residents and staff of care homes: a pragmatic cluster-randomised controlled trial
van de Ven, Geertje,
Draskovic, Irena,
Adang, Eddy M. M.,
Donders, Rogier,
Zuidema, Sytse U.,
Koopmans, Raymond T. C. M.,
Vernooij-Dassen, Myrra J. F. J.
Background: The effectiveness of dementia-care mapping (DCM) for institutionalised people with dementia has been demonstrated in an explanatory cluster-randomised controlled trial (cRCT) with two DCM researchers carrying out the DCM intervention. In order to be able to inform daily practice, we studied DCM effectiveness in a pragmatic cRCT involving a wide range of care homes […]