Krikorian, Robert, Boespflug, Erin L., Fleck, David E., Stein, Amanda L., Wightman, Jolynne D., Shidler, Marcelle D., Sadat-Hossieny, Sara

Polyphenol compounds found in berry fruits, in particular flavonoids, have been associated with health benefits including improvement in cognition and neuronal function with aging. Concord grape juice contains polyphenols, including anthocyanins and flavanols, and previous research has shown improvement in a number of human health conditions with grape juice supplementation. In the current study, older […]

Krikorian, Robert, Nash, Tiffany A., Shidler, Marcelle D., Shukitt-Hale, Barbara, Joseph, James A.

Concord grape juice contains polyphenol compounds, which have antioxidant and anti-inflammatory properties and influence neuronal signalling. Concord grape juice supplementation has been shown to reduce inflammation, blood pressure and vascular pathology in individuals with CVD, and consumption of such flavonoid-containing foods is associated with a reduced risk for dementia. In addition, preliminary animal data have […]

Remington, R., Chan, A., Lepore, A., Kotlya, E., Shea, T. B.

Preclinical studies demonstrate that apple juice exerts multiple beneficial effects including reduction of central nervous system oxidative damage, suppression of Alzheimer’s disease (AD) hallmarks, improved cognitive performance, and organized synaptic signaling. Herein, we initiated an open-label clinical trial in which 21 institutionalized individuals with moderate-to-severe AD consumed 2 4-oz glasses of apple juice daily for […]