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This database contains 556 studies, archived under the term: "dementia"

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Effect of a non-pharmacological intervention, Voix d’Or(®), on behavior disturbances in Alzheimer disease and associated disorders

An innovative non-pharmacological intervention called Voix d’Or(®) (Golden Voice) was proposed in the Cognitive behavioral unit (CBU) of the Memory center at the Hospices civils in Lyon. Voix d’Or(®) offers eight sound activities disseminated via an audio device based on different approaches sociotherapeutic (music therapy, reminiscence, relaxation, reorientation in reality). The aim of this study […]

Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer’s disease

To evaluate correlations of pharmacological treatment with cognitive and behavioral symptoms in patients with dementia due to Alzheimer’s disease with low schooling, subjects were assessed for demographic features, neuropsychiatric symptoms, cognitive decline, functionality, caregiver burden, APOE haplotypes and pharmacological treatment. Among 217 patients, use of cholinesterase inhibitors with or without Memantine was associated with less […]

A telephone-delivered psychosocial intervention improves dementia caregiver adjustment following nursing home placement

Objective: Study the preliminary efficacy of a telephone intervention, Family Intervention: Telephone Tracking-Nursing Home (FITT-NH) for improving dementia caregivers’ adjustment following nursing home placement.; Methods: Caregivers were enrolled on average 6 weeks following the care-recipients’ placement in a nursing home. Baseline assessment included self-report measures of caregiver emotional functioning, staff-caregiver interactions, placement satisfaction, health-related quality […]

A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment–ThinkingFit: Pilot and feasibility study for a randomized controlled trial

Background: Dementia affects 35 million people worldwide and is currently incurable. Many cases may be preventable because regular participation in physical, mental and social leisure activities during middle age is associated with up to 47% dementia risk reduction. However, the majority of middle-aged adults are not active enough. MCI is therefore a clear target for […]

A videophone psychosocial intervention for dementia caregivers

Background/objectives: Available services and intervention programs for dementia caregivers are often underutilized because of issues such as cost, logistics, lack of knowledge about available services, or insufficient support from others. Information technologies offer the potential of removing these barriers and facilitating the ability of caregivers to access needed support. This project evaluated the feasibility and […]

Differential effects of current specific treatments on behavioral and psychological symptoms in patients with Alzheimer’s disease: a 12-month, randomized, open-label trial

Background: Behavioral and psychological symptoms of dementia (BPSD) occur in up to 80% of Alzheimer’s disease (AD) patients and represent one of the most common reasons for early institutionalization and increase in management costs.; Objectives: This study evaluated the effects of four drugs (memantine, donepezil, rivastigmine, galantamine) in BPSD in AD patients.; Methods: This was […]

Engaging nursing home residents with dementia in activities: The effects of modeling, presentation order, time of day, and setting characteristics

We examined the impact of setting characteristics and presentation effects on engagement with stimuli in a group of 193 nursing home residents with dementia (recruited from a total of seven nursing homes). Engagement was assessed through systematic observations using the Observational Measurement of Engagement (OME), and data pertaining to setting characteristics (background noise, light, and […]

The impact of past and present preferences on stimulus engagement in nursing home residents with dementia

Objectives: We examined engagement with stimuli in 193 nursing home residents with dementia. We hypothesized that activities and stimuli based on a person’s past and current preferences would result in more engagement than other activities/stimuli. Method: The expanded version of the self-identity questionnaire [Cohen-Mansfield, J., Golander, H. & Arheim, G. (2000)] was used to determine […]

The Comprehensive Process Model of Engagement

Background: Engagement refers to the act of being occupied or involved with an external stimulus. In dementia, engagement is the antithesis of apathy. Objective: The Comprehensive Process Model of Engagement was examined, in which environmental, personal, and stimulus characteristics impact the level of engagement. Methods: Participants were 193 residents of 7 Maryland nursing with a […]

Can persons with dementia be engaged with stimuli?

Objectives: To determine which stimuli are 1) most engaging 2) most often refused by nursing home residents with dementia, and 3) most appropriate for persons who are more difficult to engage with stimuli. Methods: Participants were 193 residents of seven Maryland nursing homes. All participants had a diagnosis of dementia. Stimulus engagement was assessed by […]

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