This database contains 556 studies, archived under the term: "dementia"
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Effects of centrally acting angiotensin converting enzyme inhibitors on functional decline in patients with Alzheimer’s disease
O'Caoimh, Rónán,
Healy, Liam,
Gao, Yang,
Svendrovski, Anton,
Kerins, David M.,
Eustace, Joseph,
Kehoe, Patrick Gavin,
Guyatt, Gordon,
Molloy, D. William
Background: Centrally acting angiotensin converting enzyme inhibitors (CACE-Is) are associated with reduced rates of cognitive decline in patients with dementia. CACE-Is may also improve exercise tolerance in functionally impaired older adults with normal cognition, suggesting that CACE-Is may positively influence activities of daily living (ADL) in dementia.; Objective: To compare rates of decline in patients […]
Cognitive output of a neuropsychological stimulation program in an elderly day care center with low educated participants: An observational study
Nunes, Maria Vânia Silva,
Pinho, Ana Almeida,
Campos, Helena Mauricio,
Abreu, Paula,
Gonçalves, Isabel Pinto,
Caldas, Alexandre Castro
Objective: In the present paper we present an observational study of the implementation of a Neuropsychological Stimulation Program at an Elderly Day Care Center in low-educated participants with very similar backgrounds concerning social economic status. Methods: The implemented program tackled several dimensions, including daily orientation sessions, cognitive stimulation sessions twice a week, followed by movement […]
Validation of the Rowland Universal Dementia Assessment Scale for multicultural screening in Danish memory clinics
Nielsen, T. Rune,
Andersen, Birgitte Bo,
Gottrup, Hanne,
Lützhøft, Jan H.,
Høgh, Peter,
Waldemar, Gunhild
Background/aims: The Rowland Universal Dementia Assessment Scale (RUDAS) is a brief cognitive screening test that was developed to detect dementia in multicultural populations. The RUDAS has not previously been validated in multicultural populations outside of Australia. The aim of this study was to evaluate the diagnostic accuracy of the RUDAS in a multicultural sample of […]
Long-term metformin usage and cognitive function among older adults with diabetes
Ng, Tze Pin,
Feng, Liang,
Yap, Keng Bee,
Lee, Tih Shih,
Tan, Chay Hoon,
Winblad, Bengt
Evidence strongly supports the important role of insulin resistance in cognitive decline and dementia and suggests that insulin sensitizers may protect against cognitive decline in diabetic and pre-diabetic individuals. Inconclusive results have been reported in clinical trials of rosiglitazone, an insulin sensitizer that also increases cardiovascular mortality risks. No study has yet reported a protective […]
Encouraging lifestyle behaviour change in mild cognitive impairment patients: Development of appropriate educational material
Neville, Charlotte E.,
McCourt, Hannah J.,
McKinley, Michelle C.,
Lowis, Carole,
Barrett, Suzanne L.,
McGuinness, Bernadette,
Todd, Stephen,
Lawlor, Brian,
Gibb, Matthew,
Coen, Robert F.,
Passmore, Anthony P.,
Woodside, Jayne V.
Objectives: A healthy lifestyle may help maintain cognitive function and reduce the risk of developing dementia. This study employed a focus group approach in order to gain insight into opinions of mild cognitive impairment (MCI) patients, caregivers (CG) and health professionals (HP) regarding lifestyle and its relationship with cognition. The qualitative data were used to […]
Efficacy of musical interventions in dementia: evidence from a randomized controlled trial
Narme, Pauline,
Clément, Sylvain,
Ehrlé, Nathalie,
Schiaratura, Loris,
Vachez, Sylvie,
Courtaigne, Bruno,
Munsch, Frédéric,
Samson, Séverine
Although musical interventions have recently gained popularity as a non-pharmacological treatment in dementia, there is still insufficient evidence of their effectiveness. To investigate this issue, a single-center randomized controlled trial was conducted with forty-eight patients with Alzheimer’s disease or mixed dementia to compare the effects of music versus cooking interventions in the emotional, cognitive, and […]
The effect of Baroque music on behavioural disturbances in patients with dementia
Nair, Balakrishnan Kichu,
Heim, Christian,
Krishnan, Chitra,
D'Este, Catherine,
Marley, John,
Attia, John
Aim: To study the effect of Baroque music in people with dementia.; Methods: Patients in a multicultural dementia-specific aged care facility were subjected to Baroque music in a cross-over study.; Results: There were significantly more behavioural disturbances during the weeks when Baroque music was played compared to control periods (0.2 more episodes per week, P […]
Foot massage and physiological stress in people with dementia: A randomized controlled trial
Moyle, Wendy,
Cooke, Marie Louise,
Beattie, Elizabeth,
Shum, David H.K.,
O’Dwyer, Siobhan T.,
Barrett, Sue,
Sung, Billy
Background: The anxiety associated with unfamiliar surroundings, the disorientation and mental confusion, and the social isolation that accompanies dementia can often create increased stress for people living in long-term care settings. Such a response is thought to affect the autonomic nervous system and result in emotional and physical symptoms of distress that may be manifested […]