Vedin, Inger, Cederholm, Tommy, Freund-Levi, Yvonne, Basun, Hans, Hjorth, Erik, Irving, Gerd Faxén, Eriksdotter-Jönhagen, Maria, Schultzberg, Marianne, Wahlund, Lars-Olof, Palmblad, Jan

Omega-3 fatty acids, e.g., dokosahexaenoic acid (DHA) and eikosapentaenoic acid (EPA), ameliorate inflammatory reactions by various mechanisms, but the role of prostaglandins remains unclear. Our aim was to determine if dietary supplementation with a DHA-rich fish oil influenced the release of PGF(2alpha) from peripheral blood mononuclear cells (PBMC). In the OmegAD study, 174 Alzheimer disease […]

Freund-Levi, Yvonne, Hjorth, Erik, Lindberg, Catharina, Cederholm, Tommy, Faxén-Irving, Gerd, Vedin, Inger, Palmblad, Jan, Wahlund, Lars-Olof, Schultzberg, Marianne, Basun, Hans, Eriksdotter-Jönhagen, Maria

Background: omega-3 fatty acids (omega-3 FAs) found in dietary fish or fish oils are anti-inflammatory agents that may influence Alzheimer’s disease (AD).; Objective: To study the effects of dietary omega-3 FA supplementation on inflammatory markers in cerebrospinal fluid (CSF) and plasma from patients with mild to moderate AD.; Methods: Thirty-five patients (70.3 +/- 8.2 years) […]

Okada, Kaoru, Kurita, Akira, Takase, Bonpei, Otsuka, Toshiaki, Kodani, Eitaro, Kusama, Yoshiki, Atarashi, Hirotsugu, Mizuno, Kyoichi

Music therapy (MT) has been used in geriatric nursing hospitals, but there has been no extensive research into whether it actually has beneficial effects on elderly patients with cerebrovascular disease (CVD) and dementia. We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catecholamine levels in elderly patients with CVD […]

Lewis, John E., McDaniel, H. Reginald, Agronin, Marc E., Loewenstein, David A., Riveros, Jorge, Mestre, Rafael, Martinez, Mairelys, Colina, Niurka, Abreu, Dahlia, Konefal, Janet, Woolger, Judi M., Ali, Karriem H.

Alzheimer’s disease (AD) is a leading killer of Americans, imparts a significant toll on the quality of life of the patient and primary caregiver, and results in inordinate costs in an already overburdened medical system. Prior studies on cholinesterase inhibitors among AD patients have shown minimal amelioration of disease symptoms and/or restoration of lost cognitive […]