This database contains 21 studies, archived under the term: "agitation"
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Managing agitated behaviour in people with Alzheimer’s disease: The role of live music
Background: Agitation due to Alzheimer’s disease (AD) presents a challenge to occupational therapists working in the older people care sector. Recently background music and music therapy have emerged as promising tools in the management of agitation in AD. This exploratory study investigated whether live music could reduce agitated behaviour in people with AD. Method: A […]
Impact of ambient bright light on agitation in dementia
Barrick, Ann Louise,
Sloane, Philip D.,
Williams, Christianna S.,
Mitchell, C. Madeline,
Connell, Bettye Rose,
Wood, Wendy,
Hickman, Susan E.,
Preisser, John S.,
Zimmerman, Sheryl
Objective: To evaluate the effect of ambient bright light therapy (BLT) on agitation among institutionalized persons with dementia. Methods: High intensity, low glare ambient lighting was installed in activity and dining areas of a state psychiatric hospital unit in North Carolina and a dementia-specific residential care facility in Oregon. The study employed a cluster-unit crossover […]
Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial)
Ballard, Clive,
Brown, Richard,
Fossey, Jane,
Douglas, Simon,
Bradley, Paul,
Hancock, Judith,
James, Ian A.,
Juszczak, Edmund,
Bentham, Peter,
Burns, Alistair,
Lindesay, James,
Jacoby, Robin,
O'Brien, John,
Bullock, Roger,
Johnson, Tony,
Holmes, Clive,
Howard, Robert
Background: Good practice guidelines state that a psychological intervention should usually precede pharmacotherapy, but there are no data evaluating the feasibility of psychological interventions used in this way. Methods: At the first stage of a randomized blinded placebo-controlled trial, 318 patients with Alzheimer disease (AD) with clinically significant agitated behavior were treated in an open […]
Relapse risk after discontinuation of risperidone in Alzheimer’s disease
Devanand, D. P.,
Mintzer, Jacobo,
Schultz, Susan K.,
Andrews, Howard F.,
Sultzer, David L.,
de la Pena, Danilo,
Gupta, Sanjay,
Colon, Sylvia,
Schimming, Corbett,
Pelton, Gregory H.,
Levin, Bruce
Background: Among patients with Alzheimer’s disease who have had a response to antipsychotic medication for psychosis or agitation-aggression, the risk of a recurrence of symptoms after discontinuation of the medication has not been established.; Methods: Patients with Alzheimer’s disease and psychosis or agitation-aggression received open-label treatment with risperidone for 16 weeks. Those who had a […]
The antipsychotic discontinuation in Alzheimer disease trial: clinical rationale and study design
Devanand, D. P.,
Mintzer, Jacobo,
Schultz, Susan,
Sultzer, David,
de la Pena, Danilo,
Gupta, Sanjay,
Colon, Sylvia,
Schimming, Corbett,
Pelton, Gregory H.,
Andrews, Howard,
Levin, Bruce
Objectives: : Research studies on the effects of discontinuing antipsychotic medications in patients with dementia have not identified specific target symptoms or response to antipsychotics prior to discontinuation. The Antipsychotic Discontinuation in Alzheimer Disease (ADAD) trial addresses these issues in a randomized, double-blind, placebo-controlled, multicenter risperidone treatment and discontinuation trial. In Phase A, AD patients […]