This database contains 1058 studies, archived under the term: "aged"
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Semantic memory training in Alzheimer’s disease
The purpose of this study was to assess the effects of semantic stimulation of Alzheimer’s patients on semantic memory comparatively to psychological support. We conducted semantic training with two target categories (musical instruments and human actions), because these concepts were massively failed in previous data collected in Alzheimer’s disease. Ten patients (57-78 year old, MMSE […]
Telephone-based, cognitive-behavioral therapy for African American dementia caregivers with depression: initial findings
Glueckauf, Robert L.,
Davis, W. Shuford,
Willis, Floyd,
Sharma, Dinesh,
Gustafson, David J.,
Hayes, Jocelyn,
Stutzman, Mary,
Proctor, James,
Kazmer, Michelle M.,
Murray, Leticia,
Shipman, Judith,
McIntyre, Vera,
Wesley, Lonnie,
Schettini, Gabriel,
Xu, Jian,
Parfitt, Francine,
Graff-Radford, Neill,
Baxter, Cynthia,
Burnett, Kathleen,
Noël, La Tonya,
Haire, Kambria,
Springer, Jane
Objectives: Discuss initial findings of a randomized clinical trial comparing the effects of telephone-based and face-to-face (f-to-f) cognitive-behavioral therapy (CBT) on changes in caregiver (CG) burden, assistance support, depression, and health status for African American (AA) CGs with depression.; Design: Pilot study using a prepost, two-group design with 14 enrolled and randomized participants.; Measures: Subjective […]
Integrative cognitive-behavioral and spiritual counseling for rural dementia caregivers with depression
Glueckauf, Robert L.,
Davis, W. Shuford,
Allen, Kay,
Chipi, Patty,
Schettini, Gabriel,
Tegen, Lance,
Jian, Xu,
Gustafson, David J.,
Maze, Janet,
Mosser, Barbara,
Prescott, Susie,
Robinson, Fay,
Short, Cindy,
Tickel, Sandra,
VanMatre, Joyce,
DiGeronimo, Thomas,
Ramirez, Carmen
Objective: Discuss initial evaluation of a program for training faith community nurses (FCNs) to conduct cognitive-behavioral and spiritual counseling (CBSC) for rural dementia caregivers (CGs), and present 2 case studies on the use of CBSC for treating depression in this population.; Study Design: Pre-post evaluation of the effectiveness of CBSC training and a case study […]
Web-based psychosocial assessment for caregivers of persons with dementia: a feasibility study
Purpose and Design: Most of the 5.4 million Americans with dementia are cared for by family members who experience care needs and time constraints. This quasi-experimental study examined the experience of using a psychosocial assessment instrument to understand caregiver needs delivered in an interview versus a self-administered web-based format.; Methods: Ten family caregivers were randomized […]
Japanese-English language equivalence of the Cognitive Abilities Screening Instrument among Japanese-Americans
Gibbons, Laura E.,
McCurry, Susan,
Rhoads, Kristoffer,
Masaki, Kamal,
White, Lon,
Borenstein, Amy R.,
Larson, Eric B.,
Crane, Paul K.
Background: The Cognitive Abilities Screening Instrument (CASI) was designed for use in cross-cultural studies of Japanese and Japanese-American elderly in Japan and the U.S.A. The measurement equivalence in Japanese and English had not been confirmed in prior studies.; Methods: We analyzed the 40 CASI items for differential item functioning (DIF) related to test language, as […]
Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease
Geschwind, M. D.,
Kuo, A. L.,
Wong, K. S.,
Haman, A.,
Devereux, G.,
Raudabaugh, B. J.,
Johnson, D. Y.,
Torres-Chae, C. C.,
Finley, R.,
Garcia, P.,
Thai, J. N.,
Cheng, H. Q.,
Neuhaus, J. M.,
Forner, S. A.,
Duncan, J. L.,
Possin, K. L.,
DeArmond, S. J.,
Prusiner, S. B.,
Miller, B. L.
Objective: To determine whether oral quinacrine increases survival in sporadic Creutzfeldt-Jakob disease (sCJD).; Methods: This NIH/National Institute on Aging-funded, double-blinded, placebo-controlled, stratified randomization treatment trial was conducted at the University of California, San Francisco from February 2005 through May 2009 (ClinicalTrials.gov, NCT00183092). Subjects were randomized (50:50) to quinacrine (300 mg daily) or placebo with inpatient […]