Calabro, Rocco Salvatore, Gervasi, Giuseppe, Baglieri, Annalisa, Furnari, Anna, Marino, Silvia, Bramanti, Placido

Background: Leukoraraiosis is worldwide considered as a part of the normal aging process, although it is strongly associated with dementia and other disabilities. The pathogenesis of leukoaraiosis still has not been thoroughly acknowledged, even though chronic ischemia with consequent arteriolosclerosis probably due to endothelial dysfunction has been suggested. Treatment focuses on prevention of lesion formation […]

Raglio, Alfredo, Oasi, Osmano, Gianotti, Marta, Manzoni, Veronica, Bolis, Silvia, Ubezio, Maria C., Gentile, Simona, Villani, Daniele, Stramba-Badiale, Marco

We assessed the effects of music therapy (MT) on behavioral and psychological symptoms (BPSD) in dementia associated with changes in physiological parameters, as heart rate (HR) and heart rate variability (HRV). Twenty subjects were randomly assigned to MT treatment or standard care; all patients underwent neuropsychological assessment and ECG Holter recordings before and after the […]

Caslake, Robert, Summers, Fiona, McConachie, Douglas, Ferris, Catriona, Gordon, Joanna, Harris, Clare, Caie, Linda, Counsell, Carl

Background: Cognitive decline is common in Parkinson’s disease (PD) but may not be adequately identified by the mini-mental state examination (MMSE), which is better suited to Alzheimer’s disease. The mini-mental Parkinson (MMP) examination is a cognitive screening tool designed in French specifically for PD. We aimed to establish the validity and reliability of the English […]