This database contains 477 studies, archived under the term: "Non-pharmacological Treatment"
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Effectiveness of a structured education reminiscence-based programme for staff on the quality of life of residents with dementia in long-stay units: a study protocol for a cluster randomised trial
O'Shea, Eamon,
Devane, Declan,
Murphy, Kathy,
Cooney, Adeline,
Casey, Dympna,
Jordan, Fionnuala,
Hunter, Andrew,
Murphy, Edel
Background: Current projections indicate that there will be a significant increase in the number of people with dementia in Ireland, from approximately 40,000 at present to 100,000 by 2036. Psychosocial interventions, such as reminiscence, have the potential to improve the quality of life of people with dementia. However, while reminiscence is used widely in dementia […]
Life- and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi): study protocol for a randomised controlled trial
Thyrian, Jochen René,
Fiß, Thomas,
Dreier, Adina,
Böwing, Georgia,
Angelow, Aniela,
Lueke, Sven,
Teipel, Stefan,
Fleßa, Steffen,
Grabe, Hans Jörgen,
Freyberger, Harald Jürgen,
Hoffmann, Wolfgang
Background: The provision of appropriate medical and nursing care for people with dementia is a major challenge for the healthcare system in Germany. New models of healthcare provision need to be developed, tested and implemented on the population level. Trials in which collaborative care for dementia in the primary care setting were studied have demonstrated […]
Dementia care management: going new ways in ambulant dementia care within a GP-based randomized controlled intervention trial
Eichler, Tilly,
Thyrian, Jochen René,
Dreier, Adina,
Wucherer, Diana,
Kohler, Leonore,
Fiß, Thomas,
Böwing, Georgia,
Michalowsky, Bernhard,
Hoffmann, Wolfgang
Background: Increasing prevalence of dementia is a major challenge for the German healthcare system. The study DelpHi-MV (“Dementia: life- and person-centered help in Mecklenburg-Western Pomerania”) aims to implement and evaluate an innovative subsidiary support system for persons with dementia (PwDs) living at home and their caregivers.; Methods: DelpHi-MV is a GP-based cluster randomized controlled intervention […]
WHEDA study: effectiveness of occupational therapy at home for older people with dementia and their caregivers–the design of a pragmatic randomised controlled trial evaluating a Dutch programme in seven German centres
Voigt-Radloff, Sebastian,
Graff, Maud,
Leonhart, Rainer,
Schornstein, Katrin,
Vernooij-Dassen, Myrra,
Olde Rikkert, Marcel,
Huell, Michael
Background: A recent Dutch mono-centre randomised controlled trial has shown that occupational therapy improves daily functioning in dementia. The aim of this present study is to compare the effects of the Dutch community occupational therapy programme with a community occupational therapy consultation on daily functioning in older people with mild or moderate dementia and their […]
Exercise rehabilitation on home-dwelling patients with Alzheimer’s disease–a randomized, controlled trial. Study protocol
Pitkälä, Kaisu H.,
Raivio, Minna M.,
Laakkonen, Marja-Liisa,
Tilvis, Reijo S.,
Kautiainen, Hannu,
Strandberg, Timo E.
Background: Besides cognitive decline, Alzheimer’s disease (AD) leads to physical disability, need for help and permanent institutional care. The trials investigating effects of exercise rehabilitation on physical functioning of home-dwelling older dementia patients are still scarce. The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on […]
Preserving cognition, quality of life, physical health and functional ability in Alzheimer’s disease: the effect of physical exercise (ADEX trial): rationale and design
Hoffmann, Kristine,
Frederiksen, Kristian S.,
Sobol, Nanna Aue,
Beyer, Nina,
Vogel, Asmus,
Simonsen, Anja Hviid,
Johannsen, Peter,
Lolk, Annette,
Terkelsen, Ole,
Cotman, Carl W.,
Hasselbalch, Steen G.,
Waldemar, Gunhild
Background: Exercise is hypothesized to improve cognition, physical performance, functional ability and quality of life, but evidence is scarce. Previous studies were of short duration, often underpowered and involving home-based light exercise programs in patients with undefined dementia. The aim of the ADEX (‘Preserving Cognition, Quality of Life, Physical Health and Functional Ability in Alzheimer’s […]
The Danish Alzheimer intervention study: rationale, study design and baseline characteristics of the cohort
WALDEMAR, G.,
Waldorff, F. B.,
Buss, D. V.,
Eckermann, A.,
Keiding, N.,
Rishøj, S.,
Siersma, V.,
Sørensen, J.,
Sørensen, L. V.,
VOGEL, A.
Background: There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics of the cohort.; Methods: The study was a 1-year multicentre randomized controlled rater-blinded trial […]
Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial
Gates, Nicola J.,
Valenzuela, Michael,
Sachdev, Perminder S.,
Singh, Nalin A.,
Baune, Bernhard T.,
Brodaty, Henry,
Suo, Chao,
Jain, Nidhi,
Wilson, Guy C.,
Wang, Yi,
Baker, Michael K.,
Williamson, Dominique,
Foroughi, Nasim,
Fiatarone Singh, Maria A.
Background: The extent to which mental and physical exercise may slow cognitive decline in adults with early signs of cognitive impairment is unknown. This article provides the rationale and methodology of the first trial to investigate the isolated and combined effects of cognitive training (CT) and progressive resistance training (PRT) on general cognitive function and […]