This database contains 291 studies, archived under the term: "Behaviour"
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Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial
Gates, Nicola J.,
Valenzuela, Michael,
Sachdev, Perminder S.,
Singh, Nalin A.,
Baune, Bernhard T.,
Brodaty, Henry,
Suo, Chao,
Jain, Nidhi,
Wilson, Guy C.,
Wang, Yi,
Baker, Michael K.,
Williamson, Dominique,
Foroughi, Nasim,
Fiatarone Singh, Maria A.
Background: The extent to which mental and physical exercise may slow cognitive decline in adults with early signs of cognitive impairment is unknown. This article provides the rationale and methodology of the first trial to investigate the isolated and combined effects of cognitive training (CT) and progressive resistance training (PRT) on general cognitive function and […]
A study protocol to investigate the management of depression and challenging behaviors associated with dementia in aged care settings
McCabe, Marita P.,
Mellor, David,
Davison, Tanya E.,
Karantzas, Gery,
von Treuer, Kathryn,
O'Connor, Daniel W.
Background: The high occurrence and under-treatment of clinical depression and behavioral and psychological symptoms of dementia (BPSD) within aged care settings is concerning, yet training programs aimed at improving the detection and management of these problems have generally been ineffective. This article presents a study protocol to evaluate a training intervention for facility managers/registered nurses […]
Use of the Tailored Activities Program to reduce neuropsychiatric behaviors in dementia: an Australian protocol for a randomized trial to evaluate its effectiveness
O'Connor, C. M.,
Clemson, L.,
Brodaty, H.,
Jeon, Y. H.,
Mioshi, E.,
Gitlin, L. N.
Background: Behavioral and psychological symptoms of dementia (BPSD) are often considered to be the greatest challenge in dementia care, leading to increased healthcare costs, caregiver burden, and placement into care facilities. With potential for pharmacological intervention to exacerbate behaviors or even lead to mortality, the development and rigorous testing of non-pharmacological interventions is vital. A […]
Effects of cognitive stimulation therapy Japanese version (CST-J) for people with dementia: a single-blind, controlled clinical trial
Yamanaka, Katsuo,
Kawano, Yoshiyuki,
Noguchi, Dai,
Nakaaki, Shutaro,
Watanabe, Norio,
Amano, Takashi,
Spector, Aimee
Objectives: Cognitive stimulation therapy (CST) has shown to have significant benefits in improving the cognitive function and quality of life (QOL) in people with mild-to-moderate dementia in a UK randomized controlled trial (RCT). We developed and examined the Japanese version of group CST (CST-J) in a single-blind, controlled clinical trial.; Method: CST-J consisting of 14 […]
Walking stabilizes cognitive functioning in Alzheimer’s disease (AD) across one year
Winchester, J.,
Dick, M.B.,
Gillen, D.,
Reed, B.,
Miller, B.,
Tinklenberg, J.,
Mungas, D.,
Chui, H.,
Galasko, D.,
Hewett, L.,
Cotman, C.W.
AD is a public health epidemic, which seriously impacts cognition, mood and daily activities; however, one type of activity, exercise, has been shown to alter these states. Accordingly, we sought to investigate the relationship between exercise and mood, in early-stage AD patients (N=104) from California, over a 1-year period. Patients completed the Mini-Mental State Examination […]
Providing activity for people with dementia in care homes: a cluster randomised controlled trial
Wenborn, Jennifer,
Challis, David,
Head, Jenny,
Miranda-Castillo, Claudia,
Popham, Carolyn,
Thakur, Ruchi,
Illes, Jacqueline,
Orrell, Martin
Background: Activity levels remain low in care homes, but activity engagement can enhance residents’ quality of life.; Aim: This study aimed to assess an occupational therapy programme designed to enable care home staff to increase activity provision.; Method: A cluster randomised controlled trial with blinded assessment of outcome was conducted. A total of 210 residents […]
Longitudinal assessment of psychotherapeutic day hospital treatment for neuropsychiatric symptoms in dementia
Weber, Kerstin,
Meiler-Mititelu, Corina,
Herrmann, François Robert,
Delaloye, Christophe,
Giannakopoulos, Panteleimon,
Canuto, Alessandra
Objective: Behavioral and psychological symptoms (BPSD) of dementia are associated with more rapid cognitive deterioration as well as increased caregiver stress. The effectiveness of psychiatric day hospital care for this condition remains disputed. We report here the assessment of a psychotherapeutic day hospital program in a series of elderly people with dementia and concomitant BPSD.; […]
The effect of music therapy compared with general recreational activities in reducing agitation in people with dementia: a randomised controlled trial
Vink, A. C.,
Zuidersma, M.,
Boersma, F.,
de Jonge, P.,
Zuidema, S. U.,
Slaets, J. P. J.
Objective: This study aimed to compare the effects of music therapy with general recreational day activities in reducing agitation in people with dementia, residing in nursing home facilities.; Methods: In a randomised controlled design, residents with dementia (n = 94) were allocated to either music therapy or recreational activities. Both music therapy and general activities were offered […]
Memantine in behavioral variant frontotemporal dementia: negative results
Vercelletto, Martine,
Boutoleau-Bretonnière, Claire,
Volteau, Christelle,
Puel, Michèle,
Auriacombe, Sophie,
Sarazin, Marie,
Michel, Bernard-François,
Couratier, Philippe,
Thomas-Antérion, Catherine,
Verpillat, Patrice,
Gabelle, Audrey,
Golfier, Véronique,
Cerato, Evelyne,
Lacomblez, Lucette
We tested the efficacy and tolerability of one-year treatment with memantine (10 mg bid) in behavioral variant frontotemporal dementia (bvFTD). BvFTD patients aged 45 to 75 years, with a Mini-Mental Status Examination (MMSE) score ≥19, were enrolled in a national, randomized, double-blind, placebo-controlled (DBPC), Phase II trial. The primary endpoint was the CIBIC-Plus (Clinician’s Interview-Based […]