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Economic evaluation of an integrated diagnostic approach for psychogeriatric patients: results of a randomized controlled trial


Wolfs, Claire A.G., Dirksen, Carmen D., Kessels, Alfons, Severens, Johan L., Verhey, Frans R.J.


Archives Of General Psychiatry, Volume: 66, No.: 3, Pages.: 313-323

Year of Publication



Context: Because of the increasing number of elderly people with dementia, the costs of dementia and dementia care are expected to grow rapidly in the coming decades. Cost-effectiveness results are relevant for decision making about new strategies in dementia care.; Objective: To evaluate the cost-effectiveness of an integrated multidisciplinary diagnostic facility for diagnosing dementia in ambulatory psychogeriatric patients.; Design: Randomized controlled trial with an economic evaluation component.; Setting: The Maastricht Evaluation of a Diagnostic Intervention for Cognitively Impaired Elderly, Maastricht University Hospital, Maastricht, the Netherlands.; Patients: A total of 137 patients who received care in the multidisciplinary diagnostic facility and 93 who received usual care.; Main Outcome Measures: Quality-adjusted life-years (QALYs) as the main outcome measure and cognition and behavioral problems as secondary outcome measures.; Results: Compared with patients receiving usual care, patients who visited the diagnostic facility gained a mean 0.05 QALY at the extra cost of euro65. The incremental cost per QALY amounted to euro1267. This point estimate lies beneath commonly accepted thresholds and is within an acceptable range of uncertainty. With regard to the secondary analyses, cost-effectiveness results showed a substantial amount of uncertainty and were therefore indecisive.; Conclusion: On the basis of the main cost-per-QALY analysis, the use of the integrated multidisciplinary diagnostic facility is cost-effective for the diagnosis and management of dementia in ambulatory patients.;

Bibtex Citation

@article{Wolfs_2009, doi = {10.1001/archgenpsychiatry.2008.544}, url = {}, year = 2009, month = {mar}, publisher = {American Medical Association ({AMA})}, volume = {66}, number = {3}, pages = {313}, author = {Claire A. G. Wolfs and Carmen D. Dirksen and Alfons Kessels and Johan L. Severens and Frans R. J. Verhey}, title = {Economic Evaluation of an Integrated Diagnostic Approach for Psychogeriatric Patients}, journal = {Arch Gen Psychiatry} }


aged, aged, 80 and over, dementia, diagnosis, diagnostic, economics, epidemiology, facility, female, humans, male, mental disorders, middle aged, neuropsychological tests, questionnaires

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Economic evaluation, Randomised Controlled Trial

Type of Outcomes

Behaviour, Cognition, Quality of Life of Person With Dementia

Type of Interventions

Diagnostic Target Identification, Non-pharmacological Treatment

Diagnostic Targets


Non-Pharmaceutical Interventions

Memory clinic / assessment centre