This site uses cookies to measure how you use the website so it can be updated and improved based on your needs and also uses cookies to help remember the notifications you’ve seen, like this one, so that we don’t show them to you again. If you could also tell us a little bit about yourself, this information will help us understand how we can support you better and make this site even easier for you to use and navigate.

Early intervention for mild cognitive impairment: a randomised controlled trial


Kinsella, G. J., Mullaly, E., Rand, E., Ong, B., Burton, C., Price, S., Phillips, M., Storey, E.


Journal Of Neurology, Neurosurgery, And Psychiatry, Volume: 80, No.: 7, Pages.: 730-736

Year of Publication



Background: Positive effects are reported for memory training for healthy older adults, and yet there is limited information about the benefit of cognitive intervention for older adults with increasing memory difficulties-mild cognitive impairment.; Objective: To investigate the usefulness of an early cognitive intervention for the memory difficulties experienced by people with amnestic mild cognitive impairment.; Methods: Using a randomised control design, 52 participants with amnestic mild cognitive impairment and their family partners were randomly assigned to a cognitive intervention (memory rehabilitation group) or waitlist (control group). Participants were assessed on primary measures of everyday memory (prospective memory) and memory strategies at 2 weeks’ and 4 months’ follow-up; secondary measures of contentment with memory and the family participants’ knowledge of memory strategies were also assessed.; Results: Everyday memory, measured by performance on prospective memory tasks, significantly improved following intervention, although self-appraisal of everyday memory did not demonstrate a similar intervention effect. Knowledge and use of memory strategies also significantly increased following intervention. Furthermore, family knowledge of memory strategies increased following intervention. There was a strong trend towards improvement in contentment with memory immediately following intervention, but this effect was not significant.; Conclusions: Early intervention for memory difficulties in amnestic mild cognitive impairment, using cognitive rehabilitation in compensatory strategies, can assist in minimising everyday memory failures as evaluated by performance on prospective memory tasks and knowledge of memory strategies.;

Bibtex Citation

@article{Kinsella_2009, doi = {10.1136/jnnp.2008.148346}, url = {}, year = 2009, month = {mar}, publisher = {{BMJ}}, volume = {80}, number = {7}, pages = {730--736}, author = {G J Kinsella and E Mullaly and E Rand and B Ong and C Burton and S Price and M Phillips and E Storey}, title = {Early intervention for mild cognitive impairment: a randomised controlled trial}, journal = {Journal of Neurology, Neurosurgery {&} Psychiatry} }


aged, aged, 80 and over, amnesia, analysis of variance, cognition disorders, cognitive therapy, female, humans, male, memory, methods, neuropsychological tests, psychology, psychomotor performance, questionnaires, therapy, time factors, treatment outcome

Countries of Study


Types of Dementia

Mild Cognitive Impairment (MCI)

Types of Study

Randomised Controlled Trial

Type of Outcomes


Type of Interventions

Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Adult safeguarding and abuse detection/prevention