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This database contains 14 studies, archived under the term: "beneficial effects"

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The PACE study: a randomized clinical trial of cognitive activity strategy training for older people with mild cognitive impairment
Objective: The role of cognition-focused interventions in reducing cognitive decline in older people remains uncertain. This study aimed to clarify whether a group cognitive activity (CA) strategy-training program would decrease the 2-year rate of cognitive decline of people with mild cognitive impairment (MCI).; Design: Randomized controlled trial.; Setting: One study site.; Participants: 160 older adults […]

Reducción del malestar psicológico y de la sobrecarga en familiares cuidadores de enfermos de Alzheimer mediante la aplicación de un programa de entrenamiento en mindfulness (conciencia plena). = Reducing psychological discomfort and overload in Alzheimer’s family caregivers through a mindfulness meditation program
Introduction: This study analyzes the effects that a mindfulness development meditation program has on psychological discomfort and overload in main family caregivers of Alzheimer dementia patients. Material and methods: A quasi-experimental (group comparison) design with pretest/post-test/follow-up measurements was employed in an experimental and a control group. The evaluation instruments used were the SCL-90-R Questionnaire and […]

The study protocol of a cluster-randomised controlled trial of family-mediated personalised activities for nursing home residents with dementia
Background: Following admission to a nursing home, the feelings of depression and burden that family carers may experience do not necessarily diminish. Additionally, they may experience feelings of guilt and grief for the loss of a previously close relationship. At the same time, individuals with dementia may develop symptoms of depression and agitation (BPSD) that […]

Passive movement therapy in severe paratonia: a multicenter randomized clinical trial
Background: Paratonia causes severe movement dysfunction in late stage dementia. Passive Movement Therapy (PMT) is often used to decrease high muscle tone, but the efficacy has never been shown. The objective of this study is to investigate the effect of PMT on muscle tone after two and four weeks of treatment.; Methods: This study comprised […]

Effects of yokukansan on behavioral and psychological symptoms of vascular dementia: an open-label trial
Previous clinical trials suggest that the traditional Japanese medicine yokukansan has beneficial effects on the behavioral and psychological symptoms of dementia (BPSD). The present study was conducted to elucidate the efficacy of yokukansan on BPSD in patients with vascular dementia. Thirteen Japanese patients (9 men and 4 women) who were diagnosed as having vascular dementia […]

The ASCOMALVA trial: association between the cholinesterase inhibitor donepezil and the cholinergic precursor choline alphoscerate in Alzheimer’s disease with cerebrovascular injury: interim results
Background: Cholinesterase inhibitors (ChE-Is) are among the drugs more largely used for the treatment of mild-to-moderate symptoms of Alzheimer’s disease (AD), but beneficial long-term effects of these compounds on the cognitive, functional, and behavioural symptoms of the disease are small and not always apparent in practice. Preclinical investigations have suggested that association between ChE-Is and […]

Can a tailored exercise and home hazard reduction program reduce the rate of falls in community dwelling older people with cognitive impairment: protocol paper for the i-FOCIS randomised controlled trial
Background: The rate of falls in community dwelling older people with cognitive impairment (CI) is twice that of a cognitively intact population, with almost two thirds of people with CI falling annually. Studies indicate that exercise involving balance and/or a home hazard reduction program are effective in preventing falls in cognitively intact older people. However […]

Sustained use of CPAP slows deterioration of cognition, sleep, and mood in patients with Alzheimer’s disease and obstructive sleep apnea: a preliminary study
Introduction: Obstructive sleep apnea (OSA) is common among patients with Alzheimer’s disease (AD). Untreated OSA exacerbates the cognitive and functional deficits. Continuous positive airway pressure (CPAP) has recently been shown to have beneficial effects on cognition in AD. Little attention has focused on the long-term benefits of CPAP in these patients.; Methods: This was an […]

Quality of life of residents with dementia in traditional versus small-scale long-term care settings: a quasi-experimental study
Background: The number of people living with dementia worldwide is increasing, resulting in a need for more residential care. In response to criticism of the traditional medical approach to residential dementia care, many large nursing homes are transforming their traditional care facilities into more home-like small-scale living facilities.; Objectives: This study examined the assumed benefits […]

Day care at green care farms: a novel way to stimulate dietary intake of community-dwelling older people with dementia?
Objective: This study aimed to compare dietary intake of older people with dementia receiving day care at regular day care facilities (RDCFs) or at so-called green care farms (GCFs).; Design and Settings: A comparative cross-sectional study was performed at 10 GCFs and 10 RDCFs in the Netherlands.; Participants: 30 subjects from GCFs and 23 subjects […]

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