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This database contains 2 studies, archived under the term: "antidepressant treatment"

Discontinuation of antidepressants in people with dementia and neuropsychiatric symptoms (DESEP study): double blind, randomised, parallel group, placebo controlled trial

Objective: To determine the effect of discontinuing antidepressant treatment in people with dementia and neuropsychiatric symptoms.; Design: Double blind, randomised, parallel group, placebo controlled trial.; Setting: Norwegian nursing homes; residents recruited by 16 study centres in Norway from August 2008 to June 2010.; Participants: 128 patients with Alzheimer’s disease, dementia or vascular dementia, and neuropsychiatric […]

Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design

Treatment strategies for patients with depression and cognitive impairment (DEP-CI), who are at high risk to develop a clinical diagnosis of dementia, are not established. This issue is addressed in the donepezil treatment of cognitive impairment and depression (DOTCODE) pilot clinical trial. The DOTCODE study is the first long-term treatment trial that assesses differences in […]

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