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The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene
Snowden, Julie S.,
Hu, Quan,
Rollinson, Sara,
Halliwell, Nicola,
Robinson, Andrew,
Davidson, Yvonne S.,
Momeni, Parastoo,
Baborie, Atik,
Griffiths, Timothy D.,
Jaros, Evelyn,
Perry, Robert H.,
Richardson, Anna,
Pickering-Brown, Stuart M.,
Neary, David,
Mann, David M. A.
...a behavioural syndrome consistent with frontotemporal dementia (FTD) and severe caudate atrophy. Their cognitive/behavioural profile was distinct, characterised by prominent obsessionality, repetitive behaviours and rituals, social withdrawal and lack of...
Hostility and change in cognitive function over time in older blacks and whites
Barnes, Lisa L.,
Mendes de Leon, Carlos F.,
Bienias, Julia L.,
Wilson, Robert S.,
Everson-Rose, Susan A.,
Evans, Denis A.
...were unchanged after controlling for depressive symptoms, chronic health, neuroticism, and social and cognitive activity patterns, or when persons with cognitive impairment at baseline were excluded. The association was similar...
A home-based training program improves caregivers’ skills and dementia patients’ aggressive behaviors: a randomized controlled trial
Huang, Huei-Ling,
Kuo, Li-Min,
Chen, Yu-Shu,
Liang, Jersey,
Huang, Hsiu-Li,
Chiu, Yi-Chen,
Chen, Sien-Tsong,
Sun, Yu,
Hsu, Wen-Chuin,
Shyu, Yea-Ing L.
...written instructions and social telephone follow-ups. Behavioral problems of elderly dementia patients were assessed by the Chinese version of the Cohen-Mansfield Agitation Inventory, community form. Family caregivers’ outcomes were measured...
Efficacy and tolerability of risperidone, yokukansan, and fluvoxamine for the treatment of behavioral and psychological symptoms of dementia: a blinded, randomized trial
Teranishi, Mika,
Kurita, Masatake,
Nishino, Satoshi,
Takeyoshi, Kenji,
Numata, Yukio,
Sato, Tadahiro,
Tateno, Amane,
Okubo, Yoshiro
...social or sexual behaviors. Behavioral and psychological symptoms of dementia are seen in about 90% of patients with dementia. We aimed to compare the efficacy and tolerability of risperidone, yokukansan,...
A randomized crossover trial to study the effect of personalized, one-to-one interaction using Montessori-based activities on agitation, affect, and engagement in nursing home residents with Dementia
van der Ploeg, Eva S,
Eppingstall, Barbara,
Camp, Cameron J.,
Runci, Susannah J.,
Taffe, John,
O'Connor, Daniel W.
...showed a significantly larger reduction in agitation during the Montessori than control sessions.; Conclusion: Our results show that even non-personalized social contact can assist in settling agitated residents. Tailoring activities...
Group therapy for patients with mild cognitive impairment and their significant others: Results of a waiting-list controlled trial
Banningh, Liesbeth W. A. Joosten-Weyn,
Prins, Judith B.,
Vernooij-Dassen, Myrra J. F. J.,
Wijnen, Hugo H.,
Rikkert, Marcel G. M. Olde,
Kessels, Roy P. C.
...Background: Patients with mild cognitive impairment (MCI) have to deal with an uncertain prognosis and also face a multitude of memory-related problems and psychosocial consequences. A newly developed group...
The Coping with Caregiving Group Program for Chinese caregivers of patients with Alzheimer’s disease in Hong Kong
Au, Alma,
Li, Sapphire,
Lee, Kristy,
Leung, Patrick,
Pan, Pey-Chyou,
Thompson, Larry,
Gallagher-Thompson, Dolores
Objective: This pilot study evaluated the effectiveness of Coping with Caregiving (CWC) psychoeducational program for Chinese family caregivers of patients with Alzheimer’s disease in Hong Kong.; Method: Twenty-seven...