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Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients
Tikka, S.,
Mykkanen, K.,
Ruchoux, M.-M.,
Bergholm, R.,
Junna, M.,
Poyhonen, M.,
Yki-Jarvinen, H.,
Joutel, A.,
Viitanen, M.,
Baumann, M.,
Kalimo, H.
...provides a cost-effective guide for estimating how far one should proceed with the extensive search for a new or an uncommon mutations among the presently known over 170 different NOTCH3...
Video prompting versus other instruction strategies for persons with Alzheimer’s disease
Perilli, V.,
Lancioni, G. E.,
Hoogeveen, F.,
Caffo, A.,
Singh, N.,
O'Reilly, M.,
Sigafoos, J.,
Cassano, G.,
Oliva, D.
...and the other strategies were counterbalanced across tasks and participants and compared within alternating treatments designs.; Results: Video prompting was effective in all participants. Similarly effective were the other 2...
Specialist mental health consultation for depression in Australian aged care residents with dementia: a cluster randomized trial
McSweeney, Kate,
Jeffreys, Aimee,
Griffith, Joanne,
Plakiotis, Chris,
Kharsas, Renee,
O'Connor, Daniel W.
...Objective: This cluster randomized controlled trial sought to determine whether multidisciplinary specialist mental health consultation was more effective than care as usual in treating the depression of aged care...
Do patients diagnosed with Alzheimer’s disease benefit from a psycho-educational programme for family caregivers? A randomised controlled study
de Rotrou, Jocelyne,
Cantegreil, Inge,
Faucounau, Véronique,
Wenisch, Emilie,
Chausson, Catherine,
Jegou, David,
Grabar, Sophie,
Rigaud, Anne-Sophie
...care-recipients’ disease at M6 (0.02) was evidenced.; Conclusion: The PEP had no additional impact on patients but carers developed more effective disease understanding and ability of coping. Results support the...
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer’s disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
Dodel, Richard,
Rominger, Axel,
Bartenstein, Peter,
Barkhof, Frederik,
Blennow, Kaj,
Förster, Stefan,
Winter, Yaroslav,
Bach, Jan-Philipp,
Popp, Julius,
Alferink, Judith,
Wiltfang, Jens,
Buerger, Katharina,
Otto, Markus,
Antuono, Piero,
Jacoby, Michael,
Richter, Ralph,
Stevens, James,
Melamed, Isaac,
Goldstein, Jerome,
Haag, Stefan,
Wietek, Stefan,
Farlow, Martin,
Jessen, Frank
...Background: Three small trials suggest that intravenous immunoglobulin can affect biomarkers and symptoms of mild-to-moderate Alzheimer’s disease. We tested the safety, effective dose, and infusion interval of intravenous immunoglobulin...