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Effects of centrally acting angiotensin converting enzyme inhibitors on functional decline in patients with Alzheimer’s disease
O'Caoimh, Rónán,
Healy, Liam,
Gao, Yang,
Svendrovski, Anton,
Kerins, David M.,
Eustace, Joseph,
Kehoe, Patrick Gavin,
Guyatt, Gordon,
Molloy, D. William
...Background: Centrally acting angiotensin converting enzyme inhibitors (CACE-Is) are associated with reduced rates of cognitive decline in patients with dementia. CACE-Is may also improve exercise tolerance in functionally impaired...
Fetal striatal grafting slows motor and cognitive decline of Huntington’s disease
Paganini, M.,
Biggeri, A.,
Romoli, A. M.,
Mechi, C.,
Ghelli, E.,
Berti, V.,
Pradella, S.,
Bucciantini, S.,
Catelan, D.,
Saccardi, R.,
Lombardini, L.,
Mascalchi, M.,
Massacesi, L.,
Porfirio, B.,
Di Lorenzo, N.,
Vannelli, G. B.,
Gallina, P.
...years. Adjusted post-transplantation motor score deterioration rate was reduced compared to the pretransplantation period, and to that of not-transplanted patients by 0.9 unit/years (95% CI 0.2 to 1.6). Cognitive score...
Elder-Clowning in Long-Term Dementia Care: Results of a Pilot Study
Kontos, Pia,
Miller, Karen-Lee,
Colobong, Romeo,
Palma Lazgare, Luis I.,
Binns, Malcolm,
Low, Lee-Fay,
Surr, Claire,
Naglie, Gary
...Mansfield Agitation Inventory (CMAI), and psychiatric medication use. RESULTS: Over 12 weeks, NPI-NH scores declined significantly (t22 = -2.68, P = .01), and DCM quality-of-life scores improved significantly (F1,50 =...
Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial
Prieto-Alhambra, D.,
Judge, A.,
Arden, N. K.,
Cooper, C.,
Lyles, K. W.,
Javaid, M. K.
...status.; Methods: We used data from the Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly Recurrent Fracture Trial, of yearly intravenous 5 mg Zol vs. placebo in patients...
Lipid lowering agents, cognitive decline, and dementia: the three-city study
Ancelin, Marie-Laure,
Carrière, Isabelle,
Barberger-Gateau, Pascale,
Auriacombe, Sophie,
Rouaud, Olivier,
Fourlanos, Spiros,
Berr, Claudine,
Dupuy, Anne-Marie,
Ritchie, Karen
...cognitive functioning, visual memory, verbal fluency, psychomotor speed, and executive function), clinical diagnosis of dementia, and fibrate and statin use, were evaluated at baseline, and 2, 4, and 7 year...
Agitation in nursing home residents with dementia (VIDEANT trial): effects of a cluster-randomized, controlled, guideline implementation trial
Rapp, Michael A.,
Mell, Thomas,
Majić, Tomislav,
Treusch, Yvonne,
Nordheim, Johanna,
Niemann-Mirmehdi, Mechthild,
Gutzmann, Hans,
Heinz, Andreas
Objective: To test the effect of a complex guideline-based intervention on agitation and psychotropic prescriptions.; Design, Setting, Participants: Cluster randomized controlled trial (VIDEANT) with blinded assessment of outcome...
Psychotropic drug consumption at admission and discharge of nursing home residents
Rolland, Yves,
Andrieu, Sandrine,
Crochard, Anne,
Goni, Sylvia,
Hein, Christophe,
Vellas, Bruno
Objectives: To quantify transitions of residents into or out of nursing homes (NHs) and to describe psychotropic drug prescription at admission and discharge and with regard to dementia...
Quality of life of nursing‐home residents with dementia subject to surveillance technology versus physical restraints: An explorative study
te Boekhorst, S.,
Depla, M. F. I. A.,
Francke, A. L.,
Twisk, J. W. R.,
Zwijsen, S. A.,
Hertogh, C. M. P. M.
...Objective: As physical restraints should only be used in exceptional cases, there is an urgent need for alternatives to restraint use. Surveillance technology could be such an alternative. This...