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Rivastigmine patch ameliorates depression in mild AD: Preliminary evidence from a 6-month open-label observational study
Spalletta, Gianfranco,
Gianni, Walter,
Giubilei, Franco,
Casini, Anna R.,
Sancesario, Giuseppe,
Caltagirone, Carlo,
Cravello, Luca
...the Mini Mental State Examination, the CERAD Dysphoria scale and the modified DSM-IV criteria for MDE in AD. MDE frequency reduced significantly from the first diagnostic visit (100%) to the...
A combination of CSF tau ratio and midsaggital midbrain-to-pons atrophy for the early diagnosis of progressive supranuclear palsy
Borroni, Barbara,
Malinverno, Matteo,
Gardoni, Fabrizio,
Grassi, Mario,
Parnetti, Lucilla,
Agosti, Chiara,
Alberici, Antonella,
Premi, Enrico,
Bonuccelli, Ubaldo,
Gasparotti, Roberto,
Calabresi, Paolo,
Di Luca, Monica,
Padovani, Alessandro
...tau 33 kDa/55 kDa ratio and mid-saggital MP measure, respectively. CSF tau ratio and MP ratio were significantly reduced in PSP patients when compared to CON, CBS, and FTD (p<...
Telephone-delivered psychoeducational intervention for Hong Kong Chinese dementia caregivers: a single-blinded randomized controlled trial
Kwok, Timothy,
Wong, Bel,
Ip, Isaac,
Chui, Kenny,
Young, Daniel,
Ho, Florence
...group reduced significantly compared with caregivers in the control group. Caregivers in the intervention group also reported significantly more gain in self-efficacy in obtaining respite than the control group.; Conclusion:...
Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study
O'Callaghan, Nathan,
Parletta, Natalie,
Milte, Catherine M.,
Benassi-Evans, Bianca,
Fenech, Michael,
Howe, Peter R.C.
...associated with reduced telomere shortening (r = -0.67; P = 0.02) in the DHA group.; Conclusion: Telomeric shortening may be attenuated by ω-3 PUFA supplementation, requiring further investigation in larger...
A multidimensional home-based care coordination intervention for elders with memory disorders: the maximizing independence at home (MIND) pilot randomized trial
Samus, Quincy M.,
Johnston, Deirdre,
Black, Betty S.,
Hess, Edward,
Lyman, Christopher,
Vavilikolanu, Amrita,
Pollutra, Jane,
Leoutsakos, Jeannie-Marie,
Gitlin, Laura N,
Rabins, Peter V.,
Lyketsos, Constantine G.
...led to delays in transition from home, reduced unmet needs, and improved self-reported QOL.; Copyright © 2014 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved....
Efficacy of musical interventions in dementia: evidence from a randomized controlled trial
Narme, Pauline,
Clément, Sylvain,
Ehrlé, Nathalie,
Schiaratura, Loris,
Vachez, Sylvie,
Courtaigne, Bruno,
Munsch, Frédéric,
Samson, Séverine
...the severity of their behavioral disorders, as well as reduced caregiver distress. However, no benefit on the cognitive status of the patients was seen. While results did not demonstrate a...
Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial
Porsteinsson, Anton P.,
Drye, Lea T.,
Pollock, Bruce G.,
Devanand, D. P.,
Frangakis, Constantine,
Ismail, Zahinoor,
Marano, Christopher,
Meinert, Curtis L.,
Mintzer, Jacobo E.,
Munro, Cynthia A.,
Pelton, Gregory,
Rabins, Peter V.,
Rosenberg, Paul B.,
Schneider, Lon S.,
Shade, David M.,
Weintraub, Daniel,
Yesavage, Jerome,
Lyketsos, Constantine G.
...agitation who were receiving psychosocial intervention, the addition of citalopram compared with placebo significantly reduced agitation and caregiver distress; however, cognitive and cardiac adverse effects of citalopram may limit its...
Foot massage versus quiet presence on agitation and mood in people with dementia: A randomised controlled trial
Moyle, Wendy,
Cooke, Marie Louise,
Beattie, Elizabeth,
Shum, David H.K.,
O’Dwyer, Siobhan T.,
Barrett, Sue
...on OERS General Alertness, with a positive change in alertness for participants in the foot massage group (indicating reduced alertness) and a negative change for participants in the quiet presence...
Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial
Prieto-Alhambra, D.,
Judge, A.,
Arden, N. K.,
Cooper, C.,
Lyles, K. W.,
Javaid, M. K.
...status.; Methods: We used data from the Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly Recurrent Fracture Trial, of yearly intravenous 5 mg Zol vs. placebo in patients...
Platelet decline as a predictor of brain injury in HIV infection
Ragin, Ann B.,
D’Souza, Gypsyamber,
Reynolds, Sandra,
Miller, Eric,
Sacktor, Ned,
Selnes, Ola A.,
Martin, Eileen,
Visscher, Barbara R.,
Becker, James T.
...= 0.73-1.67) analysis. Analysis of brain volumetric data, however, indicated a relationship between platelet decline and reduced gray matter volume fraction in univariate (p = 0.06) and multivariate (p...