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A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment–ThinkingFit: Pilot and feasibility study for a randomized controlled trial
Dannhauser, Thomas M.,
Cleverley, Martin,
Whitfield, Tim J.,
Fletcher, Ben,
Stevens, Tim,
Walker, Zuzana
...Background: Dementia affects 35 million people worldwide and is currently incurable. Many cases may be preventable because regular participation in physical, mental and social leisure activities during middle age...
Task-specific training in Huntington disease: a randomized controlled feasibility trial
Quinn, L.,
Debono, K.,
Dawes, H.,
Rosser, A. E.,
Nemeth, A. H.,
Rickards, H.,
Tabrizi, S. J.,
Quarrell, O.,
Trender-Gerhard, I.,
Kelson, M. J.,
Townson, J.,
Busse, M.
...enrolled and randomly assigned to study groups.; Intervention: Task-specific training was conducted by physical therapists in participants’ homes, focusing on walking, sit-to-stand transfers, and standing, twice a week for 8...
Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial
Pitkälä, Kaisu H.,
Pöysti, Minna M.,
Laakkonen, Marja-Liisa,
Tilvis, Reijo S.,
Savikko, Niina,
Kautiainen, Hannu,
Strandberg, Timo E.
...Importance: Few rigorous clinical trials have investigated the effectiveness of exercise on the physical functioning of patients with Alzheimer disease (AD).; Objectives: To investigate the effects of intense and...
Chronic endurance exercise training prevents aging-related cognitive decline in healthy older adults: A randomized controlled trial
Muscari, Antonio,
Giannoni, Claudia,
Pierpaoli, Lucia,
Berzigotti, Annalisa,
Maietta, Pasqualino,
Foschi, Elia,
Ravaioli, Carlo,
Poggiopollini, Guido,
Bianchi, Giampaolo,
Magalotti, Donatella,
Tentoni, Claudio,
Zoli, Marco
Objective: To evaluate the effects of endurance exercise training (EET) on the cognitive status of healthy community-dwelling older adults. Methods: A randomized controlled trial was conducted involving community-dwelling...