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A pilot study on the use of interferon beta-1a in early Alzheimer’s disease subjects
Grimaldi, Luigi Maria,
Zappalà, Giuseppe,
Iemolo, Francesco,
Castellano, Anna,
Ruggieri, Stefano,
Bruno, Giuseppe,
Paolillo, Andrea
...cognitive decline in MS patients, has never been used in AD. We evaluated the safety and efficacy of IFNβ1a in subjects affected by mild-to-moderate AD in a double-blind, randomized, placebo-controlled,...
Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use
Jacobs, Emily G.,
Kroenke, Candyce,
Lin, Jue,
Epel, Elissa S.,
Kenna, Heather A.,
Blackburn, Elizabeth H.,
Rasgon, Natalie L.
...found in non-carriers. The results suggest that hormone use might buffer against accelerated cell aging in mid-life women at risk for dementia. Importantly, for non-carrier women there was no evidence...
Ingestion of Chlorella reduced the oxidation of erythrocyte membrane lipids in senior Japanese subjects
Miyazawa, Taiki,
Nakagawa, Kiyotaka,
Takekoshi, Hideo,
Higuchi, Ohki,
Kato, Shunji,
Kondo, Momoko,
Kimura, Fumiko,
Miyazawa, Teruo
Accumulation of phospholipid hydroperoxide (PLOOH) in erythrocyte membranes is an abnormality found in patients with senile dementia, including those with Alzheimer’s disease. In our previous studies, dietary xanthophylls...
Orengedoku-to augmentation in cases showing partial response to yokukan-san treatment: A case report and literature review of the evidence for use of these Kampo herbal formulae
Okamoto, Hideki,
Chino, Atsushi,
Hirasaki, Yoshiro,
Ueda, Keigo,
Iyo, Masaomi,
Namiki, Takao
...to be stopped because of extrapyramidal symptoms. In the second case, a 44-year-old man with methamphetamine-induced psychosis had suffered from serious tardive dystonia for 2 years. No conventional approach had...
A brief neuropsychological battery for use in the chronic heart failure population
Bauer, Lisa,
Pozehl, Bunny,
Hertzog, Melody,
Johnson, Julene,
Zimmerman, Lani,
Filipi, Mary
Background: Cognitive impairment is a recognized consequence of heart failure; however, there are no neuropsychological batteries with documented psychometric data in the chronic heart failure population.; Aims: To...
Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: a randomized controlled trial
Kersten, H.,
Molden, E.,
Tolo, I. K.,
Skovlund, E.,
Engedal, K.,
Wyller, T. B.
...Background: Observational studies report a relationship between anticholinergic drug scale (ADS) score and cognitive function. This study investigated whether a reduced ADS score improved cognitive function in a frail...