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Mental exercises for cognitive function: clinical evidence
The purpose of this study was to examine the beneficial effects of a new cognitive intervention program designed for the care and prevention of dementia, namely Learning Therapy. The training program used systematized basic problems in arithmetic and Japanese language as training tasks. In study 1, 16 individuals in the experimental group and 16 in […]
Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil
Kano, Osamu,
Ito, Hirono,
Takazawa, Takanori,
Kawase, Yuji,
Murata, Kiyoko,
Iwamoto, Konosuke,
Nagaoka, Tetsuro,
Hirayama, Takehisa,
Miura, Ken,
Nagata, Riya,
Kiyozuka, Tetsuhito,
Aoyagi, Jo,
Sato, Ryuta,
Eguchi, Teruo,
Ikeda, Ken,
Iwasaki, Yasuo
Clinical trials have shown the benefits of acetylcholinesterase inhibitors, such as donepezil and galantamine, and an N-methyl-d-aspartate receptor antagonist, memantine, in patients with Alzheimer’s disease (AD). However, little is known regarding the effects of switching from donepezil 5 mg/day to galantamine 16 or 24 mg/day, or regarding the effects of adding memantine to established therapy […]
An integrated dementia intervention for Korean older adults
Kang, Hee-Young,
Bae, Yeong-Suk,
Kim, Eun-Hee,
Lee, Kap-Soon,
Chae, Myeong-Jeong,
Ju, Ree-Aie
Called dotage in Korea, dementia is primarily characterized by cognitive impairments. Secondary manifestations include mental- emotional problems, including depression. This study was designed to examine the effects of an integrated dementia intervention for Korean older adults. The intervention is composed of cognitive stimulation training, exercise, music, art, and horticultural therapy. Participants included 38 older adults […]
Adverse drug reactions in elderly subjects hospitalized in a specialized dementia management unit
Kanagaratnam, Lukshe,
Mahmoudi, Rachid,
Novella, Jean-Luc,
Jolly, Damien,
Dramé, Moustapha,
Trenque, Thierry
Introduction: Drug prescriptions represent an actionable item in the prevention of adverse drug reactions (ADRs). The aims of this study were to identify risk factors for the occurrence of ADRs, and to describe symptoms and drug interactions. Methods: This was a longitudinal study over a period of 19 months in an acute geriatric ward specializing […]
Exploring the effectiveness of an internet-based program for reducing caregiver distress using the iCare Stress Management e-Training Program
Kajiyama, Bruno,
Thompson, Larry W.,
Eto-Iwase, Tamiko,
Yamashita, Mio,
Di Mario, John,
Marian Tzuang, Yuan,
Gallagher-Thompson, Dolores
Objective: Determine if the online iCare Stress Management e-Training Program reduces stress, bother, depression, and poor life quality for dementia family caregivers (CGs).; Method: CGs (N = 150) were randomly assigned to the iCare Condition (ICC) or to the Education/Information-Only Condition (EOC) for a 3-month period. Change in self-report measures of stress (PSS) (primary outcome), […]
Long-term effects of group therapy for patients with mild cognitive impairment and their significant others: a 6- to 8-month follow-up study
Banningh, L. W. A. J.-W.,
Roelofs, S. C. F.,
Vernooij-Dassen, M. J. F. J.,
Prins, J. B.,
Rikkert, M. G. M. O.,
Kessels, R. P. C.
The present study examines the long-term effects of a 10-session cognitive behavioural group therapy for patients with mild cognitive impairment (MCI) and their significant others 6 to 8 months after completion of the intervention. Forty-seven MCI patients and 47 significant others participated in the follow-up assessment. Results of the RAND-36, Illness Cognition Questionnaire, IQCODE, GDS-15 […]