This database contains 40 studies, archived under the term: "sensitivity and specificity"
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Detection of cognitive impairment and dementia using the animal fluency test: the DECIDE study
Sebaldt, Rolf,
Dalziel, William,
Massoud, Fadi,
Tanguay, André,
Ward, Rick,
Thabane, Lehana,
Melnyk, Peter,
Landry, Pierre-Alexandre,
Lescrauwaet, Benedicte
Objectives: To evaluate the performance of a one-minute screening test measured against a validated 10-minute screening test for mild cognitive impairment (MCI) in detecting CI in patients aged > or = 65 years with two or more vascular risk factors (VRF).; Methods: Patients (n=1523) aged 65 years or older without documented CI symptoms or dementia […]
Comparison of the memory performance index with standard neuropsychological measures of cognition
The Mild Cognitive Impairment Screen (MCIS) is a computer-based cognitive assessment designed for clinical and research use in detecting amnestic mild cognitive impairment (aMCI). Performance on the MCIS is reported as the Memory Performance Index (MPI). However, the comparability between the MPI and traditional neuropsychological tests in detecting aMCI, and in differentiating it from Alzheimer’s […]
Clock drawing in the Montreal Cognitive Assessment: recommendations for dementia assessment
Price, Catherine C.,
Cunningham, Holly,
Coronado, Nicole,
Freedland, Alana,
Cosentino, Stephanie,
Penney, Dana L.,
Penisi, Alfio,
Bowers, Dawn,
Okun, Michael S.,
Libon, David J.
Background: Clock drawing is part of the Montreal Cognitive Assessment (MoCA) test but may have administration and scoring limitations. We assessed (1) the reliability of the MoCA clock criteria relative to a published error scoring approach, (2) whether command-only administration could distinguish dementia from cognitively intact individuals and (3) the value of adding a clock […]
Impact of molecular imaging on the diagnostic process in a memory clinic
Ossenkoppele, Rik,
Prins, Niels D.,
Pijnenburg, Yolande A.L.,
Lemstra, Afina W.,
van der Flier, Wiesje M.,
Adriaanse, Sofie F.,
Windhorst, Albert D.,
Handels, Ron L.H.,
Wolfs, Claire A.G.,
Aalten, Pauline,
Verhey, Frans R.J.,
Verbeek, Marcel M.,
van Buchem, Mark A.,
Hoekstra, Otto S.,
Lammertsma, Adriaan A.,
Scheltens, Philip,
van Berckel, Bart N.M.
Background: [(11)C]Pittsburgh compound B ([(11)C]PIB) and [(18)F]-2-fluoro-2-deoxy-D-glucose ([(18)F]FDG) PET measure fibrillar amyloid-β load and glucose metabolism, respectively. We evaluated the impact of these tracers on the diagnostic process in a memory clinic population.; Methods: One hundred fifty-four patients underwent paired dynamic [(11)C]PIB and static [(18)F]FDG PET scans shortly after completing a standard dementia screening. Two-year […]
Validation of the Rowland Universal Dementia Assessment Scale for multicultural screening in Danish memory clinics
Nielsen, T. Rune,
Andersen, Birgitte Bo,
Gottrup, Hanne,
Lützhøft, Jan H.,
Høgh, Peter,
Waldemar, Gunhild
Background/aims: The Rowland Universal Dementia Assessment Scale (RUDAS) is a brief cognitive screening test that was developed to detect dementia in multicultural populations. The RUDAS has not previously been validated in multicultural populations outside of Australia. The aim of this study was to evaluate the diagnostic accuracy of the RUDAS in a multicultural sample of […]
Evaluation of Parkinson disease and Alzheimer disease with the use of neuromelanin MR imaging and (123)I-metaiodobenzylguanidine scintigraphy
Miyoshi, F.,
Ogawa, T.,
Kitao, S.- i.,
Kitayama, M.,
Shinohara, Y.,
Takasugi, M.,
Fujii, S.,
Kaminou, T.
Background and Purpose: Progressive changes in the substantia nigra pars compacta and locus ceruleus of patients with Parkinson disease and Alzheimer disease visualized by neuromelanin MRI and cardiac postganglionic sympathetic nerve function on (123)I-metaiodobenzylguanidine scintigraphy have not been fully evaluated. We compared the diagnostic value of these modalities among patients with early Parkinson disease, late […]
Screening for dementia using telephone interviews. An evaluation and reliability study of the Telephone Interview for Cognitive Status (TICS) in its modified German version
Matrisch, M.,
Trampisch, U.,
Klaaßen-Mielke, R.,
Pientka, L.,
Trampisch, H.J.,
Thiem, U.
Background: To assess cognitive impairment or dementia in epidemiologic studies using telephone interviews for data acquisition, valid, reliable and short instruments suitable for telephone administration are required. For the Telephone Interview for Cognitive Status (TICS) in its modified German version, the only instrument used in Germany so far, more data on reliability and practicability are […]
Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool
Liu, Yawu,
Mattila, Jussi,
Ruiz, Miguel Ángel Muñoz,
Paajanen, Teemu,
Koikkalainen, Juha,
van Gils, Mark,
Herukka, Sanna-Kaisa,
Waldemar, Gunhild,
Lötjönen, Jyrki,
Soininen, Hilkka
Purpose: To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI and CSF biomarkers.; Methods: Altogether 391 MCI cases (158 […]