Barnes, Deborah E., Santos-Modesitt, Wendy, Poelke, Gina, Kramer, Arthur F., Castro, Cynthia, Middleton, Laura E., Yaffe, Kristine

Importance: The prevalence of cognitive impairment and dementia are projected to rise dramatically during the next 40 years, and strategies for maintaining cognitive function with age are critically needed. Physical or mental activity alone result in relatively small, domain-specific improvements in cognitive function in older adults; combined interventions may have more global effects.; Objective: To […]

Wimo, A., Jönsson, L., Zbrozek, A.

Objective: Informal care is a significant component of the societal resource use and costs in dementia care. Thus it is fundamental that assessments of informal care are valid. Thus the aim was to analyse the validity of time estimates with the Resource Utilization in Dementia (RUD) instrument.; Design: Prospective observational study.; Setting: Community sample.; Participants: […]

Tay, Laura, Chua, Kia Chong, Chan, Mark, Lim, Wee Shiong, Ang, Yue Ying, Koh, Evonne, Chong, Mei Sian

Background: Discordance between patient- and caregiver-reported quality of life (QoL) is well recognized. This study sought to (i) identify predictors of discrepancy between patient- and caregiver-rated QoL amongst community-dwelling persons with mild-to-moderate dementia, and (ii) differentiate between patients who systematically rate their QoL lower versus those who rate their QoL higher relative to their caregiver […]

Oken, Barry S., Fonareva, Irina, Haas, Mitchell, Wahbeh, Helane, Lane, James B., Zajdel, Daniel, Amen, Alexandra

Objectives: The objectives of this study were to evaluate whether a mindfulness meditation intervention may be effective in caregivers of close relatives with dementia and to help refine the protocol for future larger trials.; Design: The design was a pilot randomized trial to evaluate the effectiveness of a mindfulness meditation intervention adapted from the Mindfulness-Based […]

Malek-Ahmadi, Michael, Davis, Kathryn, Belden, Christine M, Jacobson, Sandra, Sabbagh, Marwan N.

Background: Differentiating amnestic mild cognitive impairment (aMCI) from normal cognition is difficult in clinical settings. Self-reported and informant-reported memory complaints occur often in both clinical groups, which then necessitates the use of a comprehensive neuropsychological examination to make a differential diagnosis. However, the ability to identify cognitive symptoms that are predictive of aMCI through informant-based […]

Bauer, Lisa, Pozehl, Bunny, Hertzog, Melody, Johnson, Julene, Zimmerman, Lani, Filipi, Mary

Background: Cognitive impairment is a recognized consequence of heart failure; however, there are no neuropsychological batteries with documented psychometric data in the chronic heart failure population.; Aims: To document the psychometric properties of a brief neuropsychological battery in a chronic heart failure sample.; Methods: The Repeatable Battery for the Assessment of Neuropsychological Status, Trail Making […]