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This database contains 170 studies, archived under the term: "quality of life"

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Effectiveness of an intervention in groups of family caregivers of dependent patients for their application in primary health centers. Study protocol

Background: Although Primary Health Care (PHC) Teams are used to deal with prevention and treatment of sanitary problems in adults with chronic diseases, they usually have a lack of experience in development of psychotherapeutic interventions. However, these interventions are the ones that achieve better results to reduce symptomatology and improve emotional state of caregivers.The study […]

Assessing the relationship between health utilities, quality of life, and health care costs in Alzheimer’s disease: the CATIE-AD study

Objectives: To examine the relationship between multiple measures of health care costs and health utilities, quality of life, and other factors in Alzheimer’s Disease (AD).; Research Design: Data were obtained via caregiver proxy at baseline and 3- 6- and 9-months following study entry on 421 patients with AD who participated in the CATIE-AD trial of […]

Clinical curative effect of Shenxiong Bushen Capsule and its effect on the quality of life of patients with Vascular dementia

Objective:; To observe clinical curative effect of Shenxiong Bushen Capsule for the treatment of mild vascular dementia (VaD), and probe the partial mechanism.; Methods: With a block random, double-blinded and controled clinical research method adopted, seventy patients with VaD were randomly assigned to two groups in a ratio of 5:2, including 50 cases in the […]

Evidence-based interventions in dementia: A pragmatic cluster-randomised trial of an educational intervention to promote earlier recognition and response to dementia in primary care (EVIDEM-ED)

Background: The National Dementia Strategy seeks to enhance general practitioners’ diagnostic and management skills in dementia. Early diagnosis in dementia within primary care is important as this allows those with dementia and their family care networks to engage with support services and plan for the future. There is, however, evidence that dementia remains under-detected and […]

Development of an awareness-based intervention to enhance quality of life in severe dementia: trial platform

Background: Quality of residential care for people with severe dementia is in urgent need of improvement. One reason for this may be the assumption that people with severe dementia are unaware of what is happening to them. However, there is converging evidence to suggest that global assumptions of unawareness are inappropriate. This trial platform study […]

Evaluation of exercise on individuals with dementia and their carers: a randomised controlled trial

Background: Almost all of the 820,000 people in the UK with dementia will experience Behavioural and Psychological Symptoms of Dementia (BPSD). However, research has traditionally focused on treating cognitive symptoms, thus neglecting core clinical symptoms that often have a more profound impact on living with dementia. Recent evidence (Kales et al, 2007; Ballard et al, […]

Dementia in residential care: education intervention trial (DIRECT); protocol for a randomised controlled trial

Background: There is scope to improve the quality of life (QOL) of people with dementia living in residential care facilities (RCF). The DIRECT study will determine if delivery of education to General Practitioners (GPs) and care staff improves the quality of life of residential care recipients with cognitive impairment.; Methods/design: A prospective randomised controlled trial […]

Cost-effectiveness of post-diagnosis treatment in dementia coordinated by Multidisciplinary Memory Clinics in comparison to treatment coordinated by general practitioners: an example of a pragmatic trial

Background: With the rising number of dementia patients with associated costs and the recognition that there is room for improvement in the provision of dementia care, the question arises on how to efficiently provide high quality dementia care.; Objective: To describe the design of a study to determine multidisciplinary memory clinics’ (MMC) effectiveness and cost-effectiveness […]

Clinical observation on acupuncture combined with Yizhi Jiannao granules for treatment of Alzheimer’s disease

Objective: To observe clinical therapeutic effect of acupuncture combined with Yizhi Jiannao Granules for treatment of Alzheimer’s disease and its effects on intelligence, daily life and social activity ability.; Methods: Eighty-four cases were randomly divided into 3 groups, 28 cases in each group. The combined acupuncture and medication group was treated with acupuncture at Baihui […]

Continuous dopaminergic stimulation by Duodopa in advanced Parkinson’s disease: Efficacy and safety

Introduction: When advanced Parkinson’s disease (PD) patients experience motor complications (fluctuations and dyskinesias) despite standard oral treatment, two treatment options are available: deep brain stimulation and subcutaneous apomorphine infusion with respects of indications for each strategy. Continuous intraduodenal infusion of levodopa (Duodopa) via a gastrojejunal tube may be proposed at this stage of the disease […]

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