Schmitt, Frederick A., Farlow, Martin R., Meng, Xiangyi, Tekin, Sibel, Olin, Jason T.

Background and Objective: Rivastigmine is approved in the USA for the treatment of mild to moderate Alzheimer’s disease and Parkinson’s disease dementia (PDD). Executive function (EF) deficits are a core symptom of PDD. The current objective was to investigate the effects of rivastigmine capsules versus placebo on EF in PDD, focusing on secondary outcome measures […]

Matsuda, Osamu, Shido, Emi, Hashikai, Ayako, Shibuya, Haruka, Kouno, Mitsue, Hara, Chizuko, Saito, Masahiko

Background: Acetylcholinesterase inhibitors (i.e. donepezil) are known to benefit Alzheimer’s disease (AD) patients. However, the combined effects of acetylcholinesterase and cognitive stimulation therapy (CST) are still debated. The present study examined their combined effects on the progression of cognitive decline in AD.; Methods: The present study was a non-randomized controlled study and included two groups […]

Martín-Carrasco, Manuel, Martín, Manuel Franco, Valero, Carmelo Pelegrín, Millán, Pedro Roy, García, Celso Iglesias, Montalbán, Salvador Ros, Vázquez, Ana Luisa Gobartt, Piris, Sonia Pons, Vilanova, Montserrat Balañá

Objectives: Caregivers of patients with Alzheimer’s disease (AD) experience physical and psychological stress due to the caring experience. This study evaluated the benefits of a Psychoeducational Intervention Program (PIP) on caregiver burden in southern Europe.; Methods: A multicentre, prospective, randomised study was conducted. One hundred and fifteen caregivers of patients with clinical diagnosis of AD […]

Yubero, R., Gil, P., Paul, N., Maestú, F.

The ability to generate memory strategies is a key factor in the performance of episodic memory tasks. Whether the ability to generate memory strategies exerts an influence in the performance of memory tests in the elderly population is still a matter of debate. Here we present results from an experimental memory task (Test of Memory […]

Glueckauf, Robert L., Davis, W. Shuford, Willis, Floyd, Sharma, Dinesh, Gustafson, David J., Hayes, Jocelyn, Stutzman, Mary, Proctor, James, Kazmer, Michelle M., Murray, Leticia, Shipman, Judith, McIntyre, Vera, Wesley, Lonnie, Schettini, Gabriel, Xu, Jian, Parfitt, Francine, Graff-Radford, Neill, Baxter, Cynthia, Burnett, Kathleen, Noël, La Tonya, Haire, Kambria, Springer, Jane

Objectives: Discuss initial findings of a randomized clinical trial comparing the effects of telephone-based and face-to-face (f-to-f) cognitive-behavioral therapy (CBT) on changes in caregiver (CG) burden, assistance support, depression, and health status for African American (AA) CGs with depression.; Design: Pilot study using a prepost, two-group design with 14 enrolled and randomized participants.; Measures: Subjective […]

Garand, Linda, Rinaldo, Donna E., Alberth, Mary M., Delany, Jill, Beasock, Stacey L., Lopez, Oscar L., Reynolds, Charles F., Dew, Mary Amanda

Objective: Interventions directed at the mental health of family dementia caregivers may have limited impact when focused on caregivers who have provided care for years and report high burden levels. We sought to evaluate the mental health effects of problem-solving therapy (PST), designed for caregivers of individuals with a recent diagnosis of Mild Cognitive Impairment […]

Ducharme, F. C., Levesque, L. L., Lachance, L. M., Kergoat, M.-J., Legault, A. J., Beaudet, L. M., Zarit, S. H.

Purpose: The purpose of this experimental study was to test the efficacy of a psychoeducational individual program conceived to facilitate transition to the caregiver role following diagnosis of Alzheimer disease in a relative.; Design and Methods: Caregivers were recruited in memory clinics and randomized to an experimental group (n = 62) or a control group […]