Matrisch, M., Trampisch, U., Klaaßen-Mielke, R., Pientka, L., Trampisch, H.J., Thiem, U.

Background: To assess cognitive impairment or dementia in epidemiologic studies using telephone interviews for data acquisition, valid, reliable and short instruments suitable for telephone administration are required. For the Telephone Interview for Cognitive Status (TICS) in its modified German version, the only instrument used in Germany so far, more data on reliability and practicability are […]

Mathis, Chester A., Kuller, Lewis H., Klunk, William E., Snitz, Beth E., Price, Julie C., Weissfeld, Lisa A., Rosario, Bedda L., Lopresti, Brian J., Saxton, Judith A., Aizenstein, Howard J., McDade, Eric M., Kamboh, M. Ilyas, DeKosky, Steven T., Lopez, Oscar L.

Objective: This study examined amyloid-β (Aβ) deposition in 190 nondemented subjects aged ≥82 years to determine the proportion of Aβ-positive scans and associations with cognition, apolipoprotein E (APOE) status, brain volume, and Ginkgo biloba (Gb) treatment.; Methods: Subjects who agreed to participate had a brain magnetic resonance imaging and positron emission tomography scan with (11) […]

Martínez Romero, G., Peris Martí, J.F., Gomar Fayos, J., Navarro Gosalbez, M., Quintana Vargas, I., Muelas Tirado, J.

Objectives: Describe and evaluate atypical antipsychotics utilisation on the institutionalized elderly population of the Valencian Community and prevalence of associated metabolic alterations.; Material and Methods: Multicentre transversal descriptive study on medication utilisation and prevalence case-control of alterations of glycaemia, cholesterol and triglycerides. The statistical analysis of metabolic alterations is performed from the difference in prevalence […]

Lukas, A., Kilian, R., Hay, B., Muche, R., von Arnim, C.A.F., Otto, M., Riepe, M., Jamour, M., Denkinger, M.D., Nikolaus, T.

Background: When facing the well-known demographic development with an increasing number of people suffering from dementia, there is a need of programmes to support nursing relatives and care at home. Many support services have been established in the past few years but they are rarely used by the relatives and the patients. The purpose of […]

LoGiudice, Dina, Strivens, Edward, Smith, Kate, Stevenson, Margaret, Atkinson, David, Dwyer, Anna, Lautenschlager, Nicola, Almeida, Osvaldo A, Flicker, Leon

Aim: To describe the development and psychometric properties of the KICA (Kimberley Indigenous Cognitive Assessment) Screen.; Methods: A short 10-item version of the KICA, the KICA screen was developed from original data of 363 Aboriginal people. The KICA Screen was subsequently independently validated in a non-random sample of 55 people living in Northern Queensland.; Results: […]

Leontjevas, Ruslan, Gerritsen, Debby L, Smalbrugge, Martin, Teerenstra, Steven, Vernooij-Dassen, Myrra JFJ, Koopmans, Raymond TCM

Background: Depression in nursing-home residents is often under-recognised. We aimed to establish the effectiveness of a structural approach to its management.; Methods: Between May 15, 2009, and April 30, 2011, we undertook a multicentre, stepped-wedge cluster-randomised trial in four provinces of the Netherlands. A network of nursing homes was invited to enrol one dementia and […]

Man, David, Lee, Grace, Yu, Edwin, Yip,

Background: Improving the situation in older adults with cognitive decline and evidence of cognitive rehabilitation is considered crucial in long-term care of the elderly. The objective of this study was to implement a computerized errorless learning-based memory training program (CELP) for persons with early Alzheimer’s disease, and to compare the training outcomes of a CELP […]

Hebert, Paul L., McBean, Alexander Marshall, O'Connor, Heidi, Frank, Barbara, Good, Charles, Maciejewski, Matthew L.

Background: Centrally active (CA) angiotensin-converting enzyme inhibitors (ACEIs) are able to cross the blood–brain barrier. Small observational studies and mouse models suggest that use of CA versus non-CA ACEIs is associated with a reduced incidence of Alzheimer’s disease and related dementias (ADRD).; Objective: The aim of this research was to assess the effect of CA […]

Bartholomeyczik, S., Reuther, S., Luft, L., Nie, N. van, Meijers, J., Schols, J., Halfens, R.

Aim Of the Study: The aims of this study were to test the transfer and feasibility of a Dutch annual survey on malnutrition into German nursing homes and to gather first data about the prevalence of malnutrition, treatment and quality indicators in German resident homes.; Methods: A cross-sectional multicentre study, using a standardised multilevel instrument […]